基于扭曲的分子内电荷转移（TICT）机理的聚集诱导发光（AIE）分子，其荧光性能对环境的极性变化十分敏感，因此在生物传感器领域有广阔的应用前景。但由于缺乏构建此类分子的结构单元，目前这类化合物的数目还很少。为了开发性能优异的TICT-AIE分子，本项目以芳氧基给体单元为作为切入点，致力于开发出一种D、A单元经C-O键相连的新型TICT体系，并将其用作构建AIE体系的结构单元。通过改变受体单元、芳基及芳基上取代基的结构来调控化合物的光物理性质，开发出具有多种发光颜色的新型TICT-AIE分子，以及能在不同极性溶剂中呈现AIE活性的系列化合物，构建出可用于检测复杂体系中微环境极性的探针分子库。另外，本项目还将利用光物理性能测试、量子化学计算等手段，研究分子结构与发光性能的关系，探索这类化合物形成TICT态和产生AIE现象的机理，从而深入理解其发光过程，为新型AIE分子的设计开发提供思路。

Aggregation-induced emissive (AIE) compounds based on twisted intramolecular charge transfer (TICT) mechanism should be quite promising candidates as environmental polarity sensors due to their unique ICT character, which leads to their polarity-dependent fluorescence property. However, despite of their prospective application as bioprobes, there are quite few compounds reported to show AIE effect with TICT mechanism, which may be ascribed to the lack of effective constructive units for TICT-AIE molecules. In this project, we focus our attention on developing a novel TICT system, in which aryloxy D subunit is attached to A unit via C-O single bond. It might act as a quite powerful constructive unit for TICT-AIE compounds, since the photophysical properties could be fine-tuned facilely by altering the A unit, the aryl group, or the substituents on the aryl group. As a result, new TICT-AIE molecules with different emission color or with different threshold of fluorescence ON/OFF switching to polarity could be developed, and even libraries of environmental polarity sensors could be constructed. Furthermore, detailed investigation on the correlation between photophysical properties and molecular structure would be carried out, and DFT calculation would be performed here, so that the TICT and AIE mechanism of these compounds could be elucidated, which should be of great significance for developing novel AIE systems.