采用理论分析、数值模拟及试验验证相结合的手段，围绕建立基于响应面的模型更新混合模拟试验方法，对试验设计方法、响应面模型构建及累积误差分析等关键问题展开研究。首先，结合混合模拟试验自身特点，在前期已提出的基于均匀设计的单因素轮换法、分步因素重排列及分阶段模型更新等基础上，利用现有响应面模型构建方法，探索并提出适用于混合模拟试验的更高效、可靠的响应面模型更新方法。然后，采用混合编程方法编制程序，对不同更新参数数量及初值、不同结构参数、模型非线性程度等分别进行识别效率、识别累积误差及测量累积误差分析，综合评定所提方法的鲁棒性和灵敏度。最后，基于上述研究成果开发一套基于响应面的模型更新混合模拟试验模块，通过物理模型系统试验，验证上述研究成果的科学性和可靠性，从而提供更经济、可靠评价结构非线性性能的方法，进一步推动结构混合模拟方法的发展，为结构设计理论提供有效的技术支撑。

Combining the theoretical analysis, numerical simulations and experimental verifications, the model updating hybrid simulation method (HSM) based on response surface (RS) is established by studying on three key issues which include the design of experiment (DOE), the RS modeling method and the cumulative error. In the first place, considering the characteristics of the HSM, the uniform design-based single-factor-rotation method, the fractional steps factors relining method and the phased model updating method are presented at prophase. After that, taking advantage of the existing RS modeling method, the more efficient and reliable RS model updating method, which is appropriate for the HSM, is explored and presented. In the second place, using the mixed programming method, the numerical simulation program is compiled. By the analysis of the recognition efficiency, the recognition cumulative error and the measuring cumulative error under the different number and initial values of updating parameters, different structural parameters and different degree of nonlinear，the sensitivity and robustness of the proposed method are assessed comprehensively using the compiled numerical simulation program. Finally, based on the aboved research results, the program module for the model updating HSM based on RS is developed and at the meantime, the effectiveness and reliability are validated through the different-stage physical model tests. Through the research of this project, we will provide a more economic and reliable simulation method to assess the nonlinear seismic behavior of the structure, thus play a role in promoting the development of the HSM and providing the efficient technical support for the structural seismic design theory.