典型土壤有机污染物对作物代谢的影响及分子机制

本项目针对土壤/大气-作物系统中有机污染物的生命周期过程及生物效应研究的前沿科学问题，以作物吸收积累有机污染物、代谢转化以及对作物代谢与品质影响的分子机制为研究核心，旨在阐明土壤/大气-作物系统中有机污染物迁移转化及生物效应的微观机制及影响因素，研究重金属、纳米颗粒等对土壤典型有机污染物赋存形态、生物有效性以及作物吸收积累影响的分子机制，探讨土壤/大气-作物间抗性基因的迁移行为及影响因素。重点研究有机污染物对作物表观与遗传毒性效应及作物耐性的生物学机制、作物体内有机污染物代谢转化的分子机制及影响因素，探讨作物对有机污染物代谢转化的主控因子及关键介导基因；研究有机污染物/抗性基因对作物遗传代谢与品质的影响及分子机制。探讨有机污染物对作物代谢通路的扰动作用，从分子水平上研究作物应激反应的基因调控机制，为准确预测评价作物有机物污染的健康风险、科学制定土壤环境质量标准、保障农产品安全提供科学依据。

This project aims at the state-of-the-art scientific issue of the life cycle and biological effects of organic pollutants in soil/air-crop systems, focuses on the uptake, accumulation and metabolism of organic pollutants in crops, the impact of organic pollutants on the metabolism and quality of crops and related molecular mechanism. The objective of this project is to clarify the microscopic mechanism and influencing factors of the migration, transformation and biological effects of organic pollutants in soil/air-crop systems, reveal the influence and molecular mechanism of heavy metals, nanoparticles and so forth on the occurrence, bioavailability and accumulation of typical organic pollutants in soil, elucidate the migration behavior and influencing factors of antibiotic resistance genes in soil/air-crop systems. The project is proposed to highlight the apparent and genetic toxicity of organic pollutants in crops, the biological mechanism of crop tolerance, the molecular mechanism and influencing factors of the metabolism of organic pollutants in crops, and the primary factors and key genes controlling the metabolism of organic pollutants in crops. The project will also study the influence and mechanism of organic pollutants/antibiotic resistance genes to the genetics, metabolism and quality of crops, discuss the disturbance of organic pollutants to metabolic pathways of crops, and explore the mechanism of gene regulation. In summary, the result of this project is expected to provide scientific basis for the establishment of environmental quality standards for soil and the safety of agricultural production.