多元HFO/HFC混合工质通过各组分优势互补，既可以缓解HFC(氢氟烃)对全球变暖的不利影响，同时保障使用HFO(氢氟烯烃)的安全性，是广受关注的替代制冷工质。工质的PvTx性质对于制冷、热泵和有机朗肯循环等系统的设计和优化有重要作用，但目前对HFO/HFC体系的气液单相PvTx性质研究仍无法满足研究开发的需要。因此，本项目拟对HFO/HFC混合工质PvTx性质开展实验和理论研究，包括实验测量多组多元混合物PvTx性质，补充现有数据不足及空白；基于数理统计方法统筛选实验数据，改善由实验数据偏差所导致的误差传递现象，结合二元交互参数估算方法，构建普适性的统计缔合流体理论(SAFT)模型参数化方案，提高模型预测能力；建立有效的不确定度量化分析方法，探明主要影响因素及其对数值模拟结果整体不确定度的贡献。本项目的研究可为HFO/HFC环保混合工质的基础研究与实际工程应用提供可靠的理论和数据支撑。

HFO/HFC refrigerant mixtures have attracted great concern as refrigerant substitutes, which could availably mitigate the greenhouse effect and global climate changes, while ensuring security and economical efficiency through complementing each other. PVTx properties of working fluids play an important role for designing and optimizing practical system (such as refrigeration, heat pump and ORC systems), but current results of research from domestic and foreign scholars still cannot meet the needs for HFO/HFC mixtures development. In present project, the PVTx properties for multicomponent HFO/HFC mixtures will be further studied theoretically and experimentally in a systematic way. The PVTx data for several multicomponent HFO/HFC mixtures will be investigated, which will fill up the data gap. Based on Statistical Association Fluid Theory (SAFT), a model-based Optimal Experimental Design (OED) is introduced to find optimal experiments, which minimize the variance of the predicted properties and reduce the error propagation from experimental data points. Together with the values of estimated kij to build up a standardized critical-point based framework of SAFT. Develop an effective common approach for uncertainty quantification under this work and determine the key input parameters as well as their contributions to the uncertainties of overall outputs. Above all, the project would provide basic data and theoretical support for the foundational investigation of HFO/HFC mixtures and useful references for practical engineering application.