基于分布式心冲击图的睡眠动态血压测量机理研究
结题报告
批准号:
62001470
项目类别:
青年科学基金项目
资助金额:
24.0 万元
负责人:
邢晓曼
学科分类:
医学信息检测与处理
结题年份:
2023
批准年份:
2020
项目状态:
已结题
项目参与者:
邢晓曼
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中文摘要
睡眠动态血压趋势及其短期涨落的监测已经越来越受到重视。目前常用的无创动态血压测量技术负荷仍然较重,操作繁杂,具有很大的局限性。而心冲击图(BCG)方法测量血压具有零负荷、响应速度快、可分布式测量等优点。本项目将结合临床需求,融合血液动力学和躯体力学,通过理论模拟和仿体实验,阐明二维分布式BCG测量动态血压的机理,形成详尽的参考数据集,减少未知因素影响;通过量化传感器间的联动模式,对不规则睡姿等测量条件进行标准化映射,并在仿体实验中予以验证;通过代价函数优化,实现对于血压趋势和瞬时波动的同步稳定测量,并对模型性能进行全面评估。本项目将为零负荷的高准确度睡眠动态血压测量提供一条崭新的途径,为医学研究及居家监护提供必要的手段。
英文摘要
The measurement of long-term trends and short-term fluctuations of nocturnal dynamic blood pressure (BP) has received significant attention in recent years. At present, the commonly used non-invasive dynamic BP measurement technologies are either obtrusive or difficult to use, which severely limits their usage. Ballistocardiograph (BCG) based BP measurement is unobtrusive, fast and has two-dimensional sampling ability. This project is based on real clinical needs. By coupling hemodynamics and mechanics, the mechanism of multi-location BCG derived BP could be clarified through theoretical simulation and phantom experiments. A detailed reference data set will be formed to help future research. A standardized mapping of irregular sleeping postures will be achieved through the analysis of correlation functions between sensors, which will be validated by the phantom experiments. By optimizing the cost function, a BP estimation method with steady long-term trends and accurate short-term fluctuations could be obtained and thoroughly evaluated. This project will provide a new path for unobtrusive, high-precision nocturnal dynamic blood pressure estimation, and provide the necessary technical support for future medical research and home monitoring.
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DOI:10.3390/e25121582
发表时间:2023-11-24
期刊:Entropy (Basel, Switzerland)
影响因子:--
作者:
通讯作者:
DOI:10.1016/j.bspc.2023.105479
发表时间:2023-09-16
期刊:BIOMEDICAL SIGNAL PROCESSING AND CONTROL
影响因子:5.1
作者:Xing,Xiaoman;Li,Huan;Dong,Wen-fei
通讯作者:Dong,Wen-fei
DOI:10.3389/fphys.2023.1187561
发表时间:2023
期刊:Frontiers in physiology
影响因子:4
作者:
通讯作者:
DOI:--
发表时间:2021
期刊:医学新知
影响因子:--
作者:崔子琦;邢晓曼
通讯作者:邢晓曼
国内基金
海外基金