Identification of ST1 reveals a selection involving hitchhiking of seed morphology and oil content during soybean domestication.
Identification of ST1 reveals a selection involving hitchhiking of seed morphology and oil content during soybean domestication.
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ST1的鉴定揭示了大豆驯化过程中种子形态和含油量搭便车的选择
DOI：
10.1111/pbi.13791
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发表时间：
2022-06
影响因子：
13.8
通讯作者：
Sun, Lianjun
中科院分区：
文献类型：
--
作者：
Li, Jun;Zhang, Yuhang;Ma, Ruirui;Huang, Wenxuan;Hou, Jingjing;Fang, Chao;Wang, Lingshuang;Yuan, Zhihui;Sun, Qun;Dong, Xuehui;Hou, Yufeng;Wang, Ying;Kong, Fanjiang;Sun, Lianjun
栽培大豆（Glycine max）的种子形态和品质在驯化过程中发生了巨大的变化，但它们与选择的关系却知之甚少。在这里，我们描述了一个半显性基因座，ST 1（种子厚度1），影响种子厚度和编码UDP-D-葡萄糖醛酸4-差向异构酶，催化UDP-半乳糖醛酸生产和促进果胶生物合成。有趣的是，这种形态变化同时提高了种子含油量，这沿着由ST 1调节的糖酵解生物合成的上调，使大豆成为主要油料作物。引人注目的是，ST 1和反转控制种皮颜色形成了一个单一的选择性扫描的一部分。ST 1周围区域的结构变异分析表明，ST 1中的关键突变存在于大豆的早期野生近缘种中，含有ST 1的区域随后经历了倒位，随后在种皮颜色选择期间通过搭便车对这两个性状进行了连续选择。总之，这些结果提供了直接的证据，同时变化的种子形态和质量发生早于种皮颜色在大豆驯化过程中的变化。因此，ST 1的鉴定揭示了人类对大豆进行经验选择的关键阶段，并提供了我们的祖先基于味道改进大豆的证据。
Seed morphology and quality of cultivated soybean (Glycine max) have changed dramatically during domestication from their wild relatives, but their relationship to selection is poorly understood. Here, we describe a semi‐dominant locus, ST1 (Seed Thickness 1), affecting seed thickness and encoding a UDP‐D‐glucuronate 4‐epimerase, which catalyses UDP‐galacturonic acid production and promotes pectin biosynthesis. Interestingly, this morphological change concurrently boosted seed oil content, which, along with up‐regulation of glycolysis biosynthesis modulated by ST1, enabled soybean to become a staple oil crop. Strikingly, ST1 and an inversion controlling seed coat colour formed part of a single selective sweep. Structural variation analysis of the region surrounding ST1 shows that the critical mutation in ST1 existed in earlier wild relatives of soybean and the region containing ST1 subsequently underwent an inversion, which was followed by successive selection for both traits through hitchhiking during selection for seed coat colour. Together, these results provide direct evidence that simultaneously variation for seed morphology and quality occurred earlier than variation for seed coat colour during soybean domestication. The identification of ST1 thus sheds light on a crucial phase of human empirical selection in soybeans and provides evidence that our ancestors improved soybean based on taste.
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影响因子：
3
作者：
Langfelder P;Horvath S
通讯作者：
Horvath S
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影响因子：
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Wang, Yin-Zheng
影响因子：
56.9
作者：
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影响因子：
4.3
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