Parental and household smoking and the increased risk of bronchitis, bronchiolitis and other lower respiratory infections in infancy: systematic review and meta-analysis.
Parental and household smoking and the increased risk of bronchitis, bronchiolitis and other lower respiratory infections in infancy: systematic review and meta-analysis.
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DOI：
10.1186/1465-9921-12-5
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发表时间：
2011-01-10
影响因子：
5.8
通讯作者：
Leonardi-Bee J
中科院分区：
文献类型：
--
作者：
Jones LL;Hashim A;McKeever T;Cook DG;Britton J;Leonardi-Bee J
被动吸烟会增加婴儿下呼吸道感染（LRI）的风险，但近十年来有关这一关联的大量文献尚未得到系统的回顾。本文的目的是对两岁及以下婴儿被动吸烟与LRI之间的关系以及包括毛细支气管炎在内的诊断亚类别的研究进行最新的系统综述和荟萃分析。我们检索了MEDLINE和EMBASE（截至2010年11月），出版物的参考文献列表和主要会议记录的摘要，以确定所有相关出版物。估计随机效应合并优势比（OR）和95%置信区间（CI）。我们确定了60项适合纳入meta分析的研究。父母或其他家庭成员吸烟显著增加LRI的风险；父亲吸烟的比值比为1.22 (95% CI 1.10 ~ 1.35)，父母双方吸烟的比值比为1.62 (95% CI 1.38 ~ 1.89)，任何家庭成员吸烟的比值比为1.54 （95% CI 1.40 ~ 1.69）。产前母亲吸烟（OR 1.24, 95% CI 1.11 ~ 1.38）的影响弱于产后吸烟（OR 1.58, 95% CI 1.45 ~ 1.73）。最强烈的影响是毛细支气管炎，任何家庭吸烟的风险增加了2.51 （95% CI 1.96至3.21）。家庭被动吸烟是婴儿LRI风险的主要影响因素，尤其是毛细支气管炎。与产后母亲吸烟有关的风险尤其大。预防幼儿被动接触烟雾的战略是公共和儿童健康的紧急优先事项。
Passive smoke exposure increases the risk of lower respiratory infection (LRI) in infants, but the extensive literature on this association has not been systematically reviewed for nearly ten years. The aim of this paper is to provide an updated systematic review and meta-analysis of studies of the association between passive smoking and LRI, and with diagnostic subcategories including bronchiolitis, in infants aged two years and under. We searched MEDLINE and EMBASE (to November 2010), reference lists from publications and abstracts from major conference proceedings to identify all relevant publications. Random effect pooled odds ratios (OR) with 95% confidence intervals (CI) were estimated. We identified 60 studies suitable for inclusion in the meta-analysis. Smoking by either parent or other household members significantly increased the risk of LRI; odds ratios (OR) were 1.22 (95% CI 1.10 to 1.35) for paternal smoking, 1.62 (95% CI 1.38 to 1.89) if both parents smoked, and 1.54 (95% CI 1.40 to 1.69) for any household member smoking. Pre-natal maternal smoking (OR 1.24, 95% CI 1.11 to 1.38) had a weaker effect than post-natal smoking (OR 1.58, 95% CI 1.45 to 1.73). The strongest effect was on bronchiolitis, where the risk of any household smoking was increased by an OR of 2.51 (95% CI 1.96 to 3.21). Passive smoking in the family home is a major influence on the risk of LRI in infants, and especially on bronchiolitis. Risk is particularly strong in relation to post-natal maternal smoking. Strategies to prevent passive smoke exposure in young children are an urgent public and child health priority.
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影响因子：
6.3
作者：
GARDNER, G;FRANK, AL;TABER, LH
通讯作者：
TABER, LH
影响因子：
6.1
作者：
ARSHAD, SH;STEVENS, M;HIDE, DW
通讯作者：
HIDE, DW
DOI：
10.1111/j.1651-2227.1987.tb10555.x
发表时间：
1987-09-01
期刊：
ACTA PAEDIATRICA SCANDINAVICA
影响因子：
--
作者：
BISGAARD, H;DALGAARD, P;NYBOE, J
通讯作者：
NYBOE, J
影响因子：
3.3
作者：
Bonu, S;Rani, M;Nguyen, SN
通讯作者：
Nguyen, SN
影响因子：
6.3
作者：
BURR, ML;MISKELLY, FG;VAUGHANWILLIAMS, E
通讯作者：
VAUGHANWILLIAMS, E