The fibrillar collagen family.
The fibrillar collagen family.
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DOI：
10.3390/ijms11020407
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发表时间：
2010-01-28
影响因子：
5.6
通讯作者：
Lethias C
中科院分区：
文献类型：
--
作者：
Exposito JY;Valcourt U;Cluzel C;Lethias C
胶原蛋白，或更准确地说，基于胶原蛋白的细胞外基质，通常被认为是后生动物的标志。在胶原蛋白中，纤维状胶原蛋白从海绵到人类都存在，并且参与众所周知的横纹原纤维的形成。在这篇综述中，我们讨论了这个蛋白质家族的进化的不同步骤，从一个祖先的纤维胶原蛋白基因的形成，形成不同的分支。来自后鼻孔鞭毛虫（后生动物的姐妹群）短颈单囊藻（Monosiga brevicollis）和双胚层动物的基因组数据表明，祖先α链的形成发生在后生动物辐射之前。系统发生学研究表明，最早在哺乳动物中描述的三个分支的早期出现。因此，导致A、B和C分支形成的复制事件发生在真后生动物辐射之前。另一个重要的事件是两轮“全基因组复制”导致纤维胶原基因数量的扩增，以及这种多样化在发育过程中的重要性。我们还将讨论纤维胶原蛋白演变的一些其他方面，如前胶原分子和横纹原纤维形成的分子机制的发展。
Collagens, or more precisely collagen-based extracellular matrices, are often considered as a metazoan hallmark. Among the collagens, fibrillar collagens are present from sponges to humans, and are involved in the formation of the well-known striated fibrils. In this review we discuss the different steps in the evolution of this protein family, from the formation of an ancestral fibrillar collagen gene to the formation of different clades. Genomic data from the choanoflagellate (sister group of Metazoa) Monosiga brevicollis, and from diploblast animals, have suggested that the formation of an ancestral α chain occurred before the metazoan radiation. Phylogenetic studies have suggested an early emergence of the three clades that were first described in mammals. Hence the duplication events leading to the formation of the A, B and C clades occurred before the eumetazoan radiation. Another important event has been the two rounds of “whole genome duplication” leading to the amplification of fibrillar collagen gene numbers, and the importance of this diversification in developmental processes. We will also discuss some other aspects of fibrillar collagen evolution such as the development of the molecular mechanisms involved in the formation of procollagen molecules and of striated fibrils.
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影响因子：
4.8
作者：
Cluzel, C;Lethias, C;Exposito, JY
通讯作者：
Exposito, JY
影响因子：
4
作者：
DeSalle, Rob;Schierwater, Bernd
通讯作者：
Schierwater, Bernd
DOI：
10.1016/s0006-291x(79)80024-8
发表时间：
1979-01-01
影响因子：
3.1
作者：
BURGESON, RE;HOLLISTER, DW
通讯作者：
HOLLISTER, DW
影响因子：
5.6
作者：
DION, AS;MYERS, JC
通讯作者：
MYERS, JC
影响因子：
6.9
作者：
Exposito, JY;Cluzel, C;Garrone, R
通讯作者：
Garrone, R