Mycobacterium tuberculosis genotype and case notification rates, rural Vietnam, 2003-2006.
Mycobacterium tuberculosis genotype and case notification rates, rural Vietnam, 2003-2006.
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DOI：
10.3201/eid1510.090170
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发表时间：
2009-10
影响因子：
11.8
通讯作者：
Cobelens FG
中科院分区：
文献类型：
--
作者：
Buu TN;Huyen MN;Lan NN;Quy HT;Hen NV;Zignol M;Borgdorff MW;van Soolingen D;Cobelens FG
Young adults may be introducing Beijing strains. Tuberculosis case notification rates (CNRs) for young adults in Vietnam are increasing. To determine whether this finding could reflect emergence of Mycobacterium tuberculosis Beijing genotype, we studied all new sputum smear–positive pulmonary tuberculosis patients registered for treatment in 3 rural districts in Vietnam during 2003–2006. Beijing strain infections were more frequent in younger patients (15–24 years of age, 53%) than in older patients (31%; p<0.001). The increase in CNRs for youngest patients was larger for disease caused by the Beijing genotype than by other genotypes, but the difference was not significant. For patients 15–24 years of age, 85% of fluctuations in CNRs between years was caused by fluctuations in Beijing genotype infections compared with 53% and 23% in the groups 25–64 and >65 years of age, respectively (p<0.001). These findings suggest that young adults may be responsible for introducing Beijing strains into rural Vietnam.
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影响因子：
9.4
作者：
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通讯作者：
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9.4
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4.2
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Sola C
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影响因子：
11.8
作者：
Kremer K;van-der-Werf MJ;Au BK;Anh DD;Kam KM;van-Doorn HR;Borgdorff MW;van-Soolingen D
通讯作者：
van-Soolingen D
影响因子：
105.7
作者：
Baltussen, R;Floyd, K;Dye, C
通讯作者：
Dye, C