Helicobacter pylori infection in Nigerians with dyspepsia.
Helicobacter pylori infection in Nigerians with dyspepsia.
复制标题
患有消化不良的尼日利亚人幽门螺杆菌感染。
作者：
A. Olokoba;W. Gashau;S. Bwala;A. Adamu;F. Salawu
背景
幽门螺杆菌（Helicobacter pylori，Hp）是最常见的慢性细菌性感染，是酸性消化道疾病和胃癌的重要致病因素。消化不良是一种常见的胃肠道疾病，也是胃镜检查最常见的适应症。在内窥镜检查过程中检测该微生物已成为标准临床实践。我们确定了H.消化不良患者幽门螺杆菌感染的血清学和组织学研究。
方法
消化不良患者接受胃镜检查，并从胃窦部分进行活检和处理。血清标本进行H.幽门螺杆菌感染用ELISA检测抗体。
结果
研究了125例患者，包括49例（39.2%）男性和76例（60.8%）女性。H. pylori的检出率为80.0%。
结论
H.幽门螺杆菌感染的消化不良患者，和高比例的检测血清学和组织学试验。
BACKGROUND
Helicobacter pylori is the most common chronic bacterial infection, and a significant aetiological factor in acid peptic diseases and gastric cancer. Dyspepsia is a common gastrointestinal disorder, and the most common indication for gastroscopy. Detection of this organism during endoscopy has become standard clinical practice. We determine the prevalence of H. pylori infection among dyspeptic patients using serology and histology.
METHODS
Patients with dyspepsia underwent gastroscopy, and biopsies were taken from the antral portions of their stomach and processed. Their serum samples were tested for H. pylori infection using ELISA to detect anti-bodies.
RESULTS
One hundred and twenty-five patients, comprising 49 (39.2%) males and 76 (60.8%) females were studied. A prevalence rate of 93.6% for H. pylori was found by serology while a rate of 80.0% was found by histology.
CONCLUSION
There is a high prevalence of H. pylori infection in patients with dyspepsia; and a high percentage of detection by serological and histological tests.
影响因子：
29.4
作者：
GRAHAM, DY;MALATY, HM;ADAM, E
通讯作者：
ADAM, E