Efficacy and safety of 1,064 nm Q-switched Nd:YAG laser treatment for removing melanocytic nevi.

Efficacy and safety of 1,064 nm Q-switched Nd:YAG laser treatment for removing melanocytic nevi.
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DOI:
10.5021/ad.2012.24.2.162
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发表时间:
2012-05
影响因子:
1.6
通讯作者:
Kim SW
Kim SW
中科院分区:
医学4区
文献类型:
--
作者:
Kim YJ;Whang KU;Choi WB;Kim HJ;Hwang JY;Lee JH;Kim SW

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直到最近,去除黑色素细胞痣已经用CO2激光或Er:YAG激光进行。这些激光对去除受影响的斑点很有用。然而,斑点扩大或一些后遗症,包括凹陷或增生性疤痕,可能会发展为不必要的结果。Q开关Nd:YAG激光已被用于去除深层黑色素细胞,如太田痣或纹身。然而,以前没有实验来测试这种激光治疗黑色素细胞痣的有效性和安全性。本研究的目的是研究1,064 nm Q开关Nd:YAG激光去除黑素细胞痣(包括先天性黑素细胞痣和获得性黑素细胞痣)的有效性和安全性。2005年至2009年,2064名韩国小黑色素细胞痣患者接受了Q开关Nd:YAG激光治疗。在治疗前和治疗后6周,在相同的照明和位置拍摄高分辨率照片,以观察手术疗效。约70%的痣使用1,064 nm Q开关Nd:YAG激光治疗后,一个会话完全删除。其余30%在3次治疗中完全治愈。与CO2或Er:YAG激光治疗的结果相比,空心疤痕等后遗症的出现明显减少。使用1,064 nm Q开关Nd:YAG激光是治疗黑色素细胞痣的一种安全有效的方法。
Until recently, the removal of melanocytic nevi has been performed with a CO2 laser or Er:YAG laser. These lasers have been useful for removing affected spots. However, enlargement of spots or some sequelae, including depressed or hypertrophic scars, could develop as unwanted results. The Q-switched Nd:YAG laser has been used to remove deep-seated melanocytes, such as Ota nevus or tattoos. However, there have been no previous experiments performed to test the efficacy and safety of this laser treatment for melanocytic nevi. The objective of this study was to investigate the efficacy and safety of the 1,064 nm Q-switched Nd:YAG laser for removing melanocytic nevi, including congenital nevomelanocytic and acquired nevomelanocytic nevi. Two thousand and sixty four Korean patients with small melanocytic nevi were treated with a Q-switched Nd:YAG laser from 2005 to 2009. High-resolution photographs were taken in identical lighting and positions before and after the six weeks of treatment to observe the procedural efficacy. About 70% of the nevi treated using a 1,064 nm Q-switched Nd:YAG laser were completely removed after one session. The other 30% were completely treated within three sessions. The appearance of sequelae such as hollow scars noticeably decreased compared to the results seen in CO2 or Er:YAG laser treatments. Use of the 1,064 nm Q-switched Nd:YAG laser is a safe and effective treatment modality for melanocytic nevi.
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