Factors impacting on progress towards elimination of transmission of schistosomiasis japonica in China.
Factors impacting on progress towards elimination of transmission of schistosomiasis japonica in China.
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DOI：
10.1186/1756-3305-5-275
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发表时间：
2012-12-03
影响因子：
3.2
通讯作者：
Jiang QW
中科院分区：
文献类型：
--
作者：
Zhou YB;Liang S;Jiang QW
在过去的几十年里，中国在控制血吸虫病方面取得了巨大的进步，在5个省消除了日本血吸虫的传播，在7个流行省中显著降低了传播强度。最近，中国在整个流行地区实施了一项综合控制战略，重点关注对人和牛的干预措施。这一策略假定减少日本血吸虫从人类和牛向中间寄主钉螺的传播将最终阻断这种寄生虫的传播，并在一些流行地区取得了有效成果。然而，日本血吸虫的传播相对复杂——除了人类和牛之外，超过40种哺乳动物可以作为潜在的人畜共患病宿主。在此，我们警告说，一些因素——其他哺乳动物宿主和人类运动在维持传播中的潜在作用、当前感染诊断工具的低敏感性/特异性、吡喹酮治疗失败、环境和社会经济因素的变化（如主要流行地区的洪水）——可能对阻断寄生虫的传播构成重大障碍。需要评估这些因素在传输中的潜在作用以及对当前旨在中断传输的控制策略的影响。
Over the past decades China has made a great stride in controlling schistosomiasis, eliminating transmission of Schistosoma japonicum in 5 provinces and remarkably reducing transmission intensities in the rest of the seven endemic provinces. Recently, an integrated control strategy, which focuses on interventions on humans and bovines, has been implemented throughout endemic areas in China. This strategy assumes that a reduction in transmission of S. japonicum from humans and bovines to the intermediate Oncomelania snail host would eventually block the transmission of this parasite, and has yielded effective results in some endemic areas. Yet the transmission of S. japonicum is relatively complicated – in addition to humans and bovines, more than 40 species of mammalians can serve as potential zoonotic reservoirs. Here, we caution that some factors – potential roles of other mammalian reservoirs and human movement in sustaining the transmission, low sensitivity/specificity of current diagnostic tools for infections, praziquantel treatment failures, changes in environmental and socio-economic factors such as flooding in key endemic areas - may pose great obstacles towards transmission interruption of the parasite. Assessing potential roles of these factors in the transmission and implications for current control strategies aiming at transmission interruption is needed.
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影响因子：
3.2
作者：
Liang YS;Wang W;Li HJ;Shen XH;Xu YL;Dai JR
通讯作者：
Dai JR
DOI：
10.1016/s0035-9203(03)90112-x
发表时间：
2003-03-01
影响因子：
2.2
作者：
Li, YS;He, YK;McManus, DP
通讯作者：
McManus, DP
影响因子：
3.7
作者：
Gray DJ;Williams GM;Li Y;McManus DP
通讯作者：
McManus DP
影响因子：
9.4
作者：
Attallah, AM;Ismail, H;Ezzat, F
通讯作者：
Ezzat, F
影响因子：
56.3
作者：
Gray, Darren J.;McManus, Donald P.;Ross, Allen G.
通讯作者：
Ross, Allen G.