Role of endothelin-1 in lung disease.
Role of endothelin-1 in lung disease.
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DOI:
10.1186/rr44
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发表时间:
2001
影响因子:
5.8
通讯作者:
Rodman DM
中科院分区:
文献类型:
--
作者:
Fagan KA;McMurtry IF;Rodman DM
Endothelin-1 (ET-1) is a 21 amino acid peptide with diverse biological activity that has been implicated in numerous diseases. ET-1 is a potent mitogen regulator of smooth muscle tone, and inflammatory mediator that may play a key role in diseases of the airways, pulmonary circulation, and inflammatory lung diseases, both acute and chronic. This review will focus on the biology of ET-1 and its role in lung disease.
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