Intravital Microreflectometry of Individual Pial Vessels and Capillary Region of Rat
Intravital Microreflectometry of Individual Pial Vessels and Capillary Region of Rat
复制标题
大鼠个体软膜血管和毛细血管区域的活体微反射测量
DOI：
10.1038/jcbfm.1994.12
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发表时间：
1994
影响因子：
6.3
通讯作者：
T. Shiga
中科院分区：
文献类型：
--
作者：
Manabu Watanabe;N. Harada;H. Kosaka;T. Shiga
A microscopic reflectance spectrophotometer was constructed to obtain the spectra of single pial vessels and of a region containing only capillaries (capillary region). The difference in the oxygen saturation (So2) of hemoglobin between the regional arteriole and venule [R(A – V)] and that between the regional arteriole or capillaries [R(A – C)] were calculated. The reduction of cytochrome aa3 was also estimated in the capillary region. This method was applied to the brain surface of spontaneously breathing rats subjected to hypoxic and anemic hypoxia. On decreasing the inhaled O2 from 100 to 15%, elevation of R(A – V) and R(A – C) with slight arteriolar dilatation (though statistically not significant) was observed. Below 10% O2 (especially at 4 and 3% O2), the R(A – V) and R(A – C) decreased in spite of significant arteriolar dilatation with progressive reduction of cytochrome aa3, indicating suppression of oxygen transport to mitochondria. In the case of hemodilution down to 37% hematocrit (Ht), elevation of R(A – V) and R(A – C) occurred with a slight tendency toward arteriolar dilatation. Below 32% Ht, the R(A – V) decreased but the R(A – C) remained steady, while reduction of cytochrome aa3 progressed. Altogether, the So2 in the capillary region decreased and the reduction of cytochrome aa3 progressed with the decline of arteriolar O2 supply in both hypoxic and anemic hypoxia.
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软脑膜血管对荧光素钠通透性的体内研究：不存在缓激肽、组胺、血清素或花生四烯酸的改变。
影响因子：
8.3
作者：
Watanabe,M;Rosenblum,WI
通讯作者：
Rosenblum,WI
DOI：
10.1016/0883-9441(89)90050-6
发表时间：
1989-03
期刊：
The American journal of physiology
影响因子：
--
作者：
Aleksander S. Popel;Roland N. Pittman;M. Ellsworth
通讯作者：
Aleksander S. Popel;Roland N. Pittman;M. Ellsworth
常氧和缺氧条件下有血脑和无血脑中细胞色素氧化酶血红素铁和铜吸收的检测。
影响因子：
2.9
作者：
Miyake,H;Nioka,S;Zaman,A;Smith,DS;Chance,B
通讯作者：
Chance,B
使用冷冻分光光度法测定微血管氧合血红蛋白饱和度。
DOI：
10.1152/ajpheart.1990.259.6.h1912
发表时间：
1990
期刊：
The American journal of physiology
影响因子：
--
作者：
Fenton,BM;Gayeski,TE
通讯作者：
Gayeski,TE