Ionic-Liquid-Based Aqueous Two-Phase Systems Induced by Intra- and Intermolecular Hydrogen Bonds.
Ionic-Liquid-Based Aqueous Two-Phase Systems Induced by Intra- and Intermolecular Hydrogen Bonds.
复制标题
由分子内和分子间氢键诱导的基于离子液体的水性两相系统。
DOI：
10.3390/molecules27165307
复制
发表时间：
2022-08-19
期刊：
影响因子：
--
通讯作者：
中科院分区：
文献类型：
--
作者：
In recent years, aqueous two-phase systems (ATPSs) have been widely used in different fields and have become an increasingly attractive subject due to their application in the separation and purification of biomolecules. In this work, the aqueous phase behavior of ionic liquids (ILs) was modulated by changing the cis-trans structure of the anion in ILs. With the same tetra-butyl-phosphine as the cation, the cis-anion exhibited upper critical solution temperature (UCST) phenomena. In contrast, the trans-anion exhibited lower critical solution temperature (LCST) phenomena. The proposed mechanism shows that the main factors responsible for these phenomena include variations in the dissociation degree with temperature and the steric hindrance of the ILs. This phase behavior combines the chemical equilibrium in a solution with the microstructure of the molecule and is useful for constructing new chemical dynamic equilibria in ATPS. As an example of its application, aqueous solutions of both ILs can be used for the efficient separation and extraction of specific amino acids. The two ATPS systems reported in this work highlight a simple, effective, and environmentally friendly method for separating small biological molecules.
登录
查看更多内容
影响因子：
64.8
作者：
ALBERTSSON, PA
通讯作者：
ALBERTSSON, PA
影响因子：
4.9
作者：
Fukaya, Yukinobu;Sekikawa, Kenta;Ohno, Hiroyuki
通讯作者：
Ohno, Hiroyuki
DOI：
10.1007/10_2006_045
发表时间：
2007-01-01
期刊：
CELL SEPARATION: FUNDAMENTALS, ANALYTICAL AND PREPARATIVE METHODS
影响因子：
--
作者：
Cabral, J. M. S.
通讯作者：
Cabral, J. M. S.
影响因子：
4.1
作者：
Asenjo, Juan A.;Andrews, Barbara A.
通讯作者：
Andrews, Barbara A.
影响因子：
2.6
作者：
Pereira, Jorge F. B.;Freire, Mara G.;Coutinho, Joao A. P.
通讯作者：
Coutinho, Joao A. P.