Ensembl 2008.

Ensembl 2008.
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DOI:
10.1093/nar/gkm988
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发表时间:
2008-01
影响因子:
14.9
通讯作者:
Searle S
Searle S
中科院分区:
生物学2区
文献类型:
--
作者:
Flicek P;Aken BL;Beal K;Ballester B;Caccamo M;Chen Y;Clarke L;Coates G;Cunningham F;Cutts T;Down T;Dyer SC;Eyre T;Fitzgerald S;Fernandez-Banet J;Gräf S;Haider S;Hammond M;Holland R;Howe KL;Howe K;Johnson N;Jenkinson A;Kähäri A;Keefe D;Kokocinski F;Kulesha E;Lawson D;Longden I;Megy K;Meidl P;Overduin B;Parker A;Pritchard B;Prlic A;Rice S;Rios D;Schuster M;Sealy I;Slater G;Smedley D;Spudich G;Trevanion S;Vilella AJ;Vogel J;White S;Wood M;Birney E;Cox T;Curwen V;Durbin R;Fernandez-Suarez XM;Herrero J;Hubbard TJ;Kasprzyk A;Proctor G;Smith J;Ureta-Vidal A;Searle S

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Ensembll项目(http:www.ensembl.org)是一个综合的基因组信息系统,具有一套完整的脊索动物和选定的模式生物和疾病媒介基因组的基因组注释、数据库和其他信息。截至第47版(2007年10月),Ensembl完全支持35个物种,初步支持另外6个物种。去年的新物种包括鸭嘴兽和马。自我们上次报告以来,Ensembl的主要补充和改进包括以专门的功能基因组学数据库、蛋白质-DNA相互作用的全基因组图谱和Ensembl监管构建的形式广泛支持功能基因组学数据;通过添加用户帐户和用户组支持Ensembl Web界面的定制;以及增加对基因组重测序的支持。我们还推出了新的基于比较基因组学的数据挖掘选项,并报告了我们软件基础设施的持续发展。
The Ensembl project (http://www.ensembl.org) is a comprehensive genome information system featuring an integrated set of genome annotation, databases and other information for chordate and selected model organism and disease vector genomes. As of release 47 (October 2007), Ensembl fully supports 35 species, with preliminary support for six additional species. New species in the past year include platypus and horse. Major additions and improvements to Ensembl since our previous report include extensive support for functional genomics data in the form of a specialized functional genomics database, genome-wide maps of protein–DNA interactions and the Ensembl regulatory build; support for customization of the Ensembl web interface through the addition of user accounts and user groups; and increased support for genome resequencing. We have also introduced new comparative genomics-based data mining options and report on the continued development of our software infrastructure.
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