Natural variation in Glume Coverage 1 causes naked grains in sorghum.
Natural variation in Glume Coverage 1 causes naked grains in sorghum.
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DOI：
10.1038/s41467-022-28680-3
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发表时间：
2022-02-25
影响因子：
16.6
通讯作者：
Xie Q
中科院分区：
文献类型：
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作者：
Xie P;Tang S;Chen C;Zhang H;Yu F;Li C;Wei H;Sui Y;Wu C;Diao X;Wu Y;Xie Q
谷物脱粒过程中最关键的步骤之一是将种子从粘稠的颖片中剥离出来。裸粒与低颖片覆盖率显著提高脱粒效率和种子质量。在这里，我们证明编码非典型G蛋白γ亚基的GC1 （Glume Coverage 1）负调控高粱的颖片覆盖。自然截断的GC1 c端变异在更高的蛋白水平上积累，并影响与patin相关的磷脂酶SbpPLAII-1的稳定性。在裸高粱品种中，GC1基因区周围存在较强的正向选择特征。我们的研究结果揭示了GC1 c端变异对高粱颖片发育的微妙调控是高粱驯化过程中的一个关键事件，并为未来的裸粒育种奠定了策略。低颖片覆盖率是粮食生产中容易脱粒的首选，但遗传基础尚不清楚。作者报道了编码非典型G蛋白γ亚基的GC1基因负调控高粱颖片覆盖，自然截断的等位基因可用于裸粒育种。
One of the most critical steps in cereal threshing is the ease with which seeds are detached from sticky glumes. Naked grains with low glume coverage have dramatically increased threshing efficiency and seed quality. Here, we demonstrate that GC1 (Glume Coverage 1), encoding an atypical G protein γ subunit, negatively regulates sorghum glume coverage. Naturally truncated variations of GC1 C-terminus accumulate at higher protein levels and affect the stability of a patatin-related phospholipase SbpPLAII-1. A strong positive selection signature around the GC1 genic region is found in the naked sorghum cultivars. Our findings reveal a crucial event during sorghum domestication through a subtle regulation of glume development by GC1 C-terminus variation, and establish a strategy for future breeding of naked grains. Low glume coverage is the preferred for easy threshing in grain production, but the genetic basis remains unclear. Here, the authors report the gene GC1, which encodes an atypical G protein γ subunit, negatively regulates sorghum glume coverage and the naturally truncated alleles can be useful in the naked grain breeding.
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影响因子：
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使用下一代 DNA 测序数据进行变异发现和基因分型的框架。
影响因子：
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通讯作者：
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