Laparoscopic portal branch ligation of the right caudate lobe concomitant with portal vein embolization for planned right hemihepatectomy in advanced hepatobiliary cancers
Laparoscopic portal branch ligation of the right caudate lobe concomitant with portal vein embolization for planned right hemihepatectomy in advanced hepatobiliary cancers
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腹腔镜右尾状叶门静脉分支结扎联合门静脉栓塞治疗晚期肝胆癌计划的右半肝切除术
DOI：
10.1007/s00423-021-02147-3
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Tajima Yoshitsugu
中科院分区：
文献类型：
--
作者：
Kawabata Yasunari;Hayashi Hikota;Yoshida Rika;Ando Shinji;Nakamura Kosuke;Kishi Takashi;Nishi Takeshi;Nakamura Megumi;Tajima Yoshitsugu
背景：结扎门静脉分支至尾状叶（cPVL）作为计划肝大切除术的准备工作的作用尚不清楚。本研究的目的是评价腹腔镜cPVL （Lap-cPVL）联合经回肠结肠门静脉栓塞右门静脉系统（rTIPE），即Lap-cPVL/rTIPE在晚期肝癌患者计划右半肝切除术（rHx）中的疗效。方法在2013年3月至2020年3月期间，31例rTIPE合并/不合并lap - cpvl的患者接受了rHx治疗。右尾状叶门静脉支行lap - cpvl。结果31例患者中8例行lap - cpvl /rTIPE。lap - cpvl /rTIPE的肥厚程度（19.3%，范围6.5-25.6%）明显高于rTIPE(7.2%，范围- 1.1 - 21.2%)（p=0.027）。lap - cpvl /rTIPE的功能动力学生长率（5.40%，范围2.17 ~ 5.97）显著高于rTIPE(1.85%，范围- 0.22 ~ 6.45%)（p=0.046）。rTIPE患者术后肝衰竭≧B级发生率为21.7%，而lap - cpvl /rTIPE患者术后无肝衰竭≧B级。在本研究中，rHx术后死亡率为零。结论lap - cpvl /rTIPE对晚期胆管癌患者肝脏肥厚有一定的治疗作用。
BackgroundThe role of ligation of the portal venous branches to the caudate lobe (cPVL) as preparation for planned major hepatectomy is unclear. The aim of this study was to evaluate the efficacy of laparoscopic cPVL (Lap-cPVL) concomitant with transileocolic portal vein embolization of the right portal venous system (rTIPE), namely,Lap-cPVL/rTIPE, for planned right hemihepatectomy (rHx) in advanced hepatobiliary cancer patients.MethodsThirty-one patients who underwent rHx after rTIPE with/withoutLap-cPVL between March 2013 and March 2020 were enrolled in this study. TheLap-cPVL was performed for the portal branches of the right caudate lobe.ResultsEight of the 31 patients underwentLap-cPVL/rTIPE. The degree of hypertrophy was significantly increased inLap-cPVL/rTIPE (19.3%, range 6.5–25.6%) as compared to rTIPE (7.2%, range - 1.1 to 21.2%) (p=0.027). The functional kinetic growth rate was also significantly increased inLap-cPVL/rTIPE (5.40%, range 2.17–5.97) than that in rTIPE (1.85%, range - 0.22 to 6.45%) (p=0.046). Postoperative liver failure ≧ grade B occurred in 21.7% of patients in rTIPE, while there was no postoperative liver failure ≧ grade B inLap-cPVL/rTIPE. Mortality rates were zero after rHx in this study.ConclusionsLap-cPVL/rTIPE is safe and provides an additional effect on liver hypertrophy in advanced hepatobiliary cancers.
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孤立性肝尾状叶切除术。
影响因子：
3.8
作者：
K. Yanaga;T. Matsumata;H. Hayashi;M. Shimada;K. Urata;K. Sugimachi
通讯作者：
K. Sugimachi
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影响因子：
5.2
作者：
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影响因子：
9.6
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L. Blumgart
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DOI：
10.1016/j.jamcollsurg.2014.04.022
发表时间：
2014-10
影响因子：
5.2
作者：
Leung, Universe;Simpson, Amber L.;Araujo, Raphael L. C.;Goenen, Mithat;McAuliffe, Conor;Miga, Michael I.;Parada, E. Patricia;Allen, Peter J.;D'Angelica, Michael I.;Kingham, T. Peter;DeMatteo, Ronald P.;Fong, Yuman;Jarnagin, William R.
通讯作者：
Jarnagin, William R.
DOI：
--
发表时间：
2008
期刊：
影响因子：
--
作者：
Kimitaka Kogure.
通讯作者：
Kimitaka Kogure.