Discover of a Novel SNP Highly Associated with Chicken Blue Egg
Discover of a Novel SNP Highly Associated with Chicken Blue Egg
复制标题
发现与蓝鸡蛋高度相关的新 SNP
DOI:
10.3923/javaa.2011.92.95
复制
发表时间:
2011
影响因子:
--
通讯作者:
Deng, X. M.
中科院分区:
文献类型:
--
作者:
Wang, Z. P.;Wang, X. T.;Liu, R. F.;Wang, A. R.;Li, J. Y.;Deng, X. M.
Blue egg is caused by a dominant mutation, Oocyan (O) which is previous located on short arm of chicken chromosome 1 but precise genetic mechanism underlying blue egg is still unknown so far. In this study, we found a SNP (g.67419892-67419904del13) significantly associated with blue egg using 126 browned-shelled chickens and 202 blue-shelled chickens. The allelic and genotypic frequencies of g.67419892-67419904del13 are significantly higher in blue-shelled chickens (92.5 and 87.1%) compared with brown-shelled chickens (10.7 and 8.7%, p < 0.0001). Moreover, the genetic distance between O and g.67419892-67419904del13 is estimated to be over 2 cM (LOD = 13.51) using 149 F(2) offspring from mating between blue-shelled males and brown-shelled females. Apparently, the marker is useful for the cloning of O and marker aid selection of blue-shelled chicken breed.
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影响因子:
3.8
作者:
Wu Y;Brosh RM Jr
通讯作者:
Brosh RM Jr
影响因子:
11.8
作者:
Smits, P;Li, P;Lefebvre, V
通讯作者:
Lefebvre, V
影响因子:
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作者:
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通讯作者:
Durante, W
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作者:
Macfarlane, WM;Campbell, SC;Docherty, K
通讯作者:
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DOI:
10.1016/j.biocel.2009.07.016
发表时间:
2010-03
影响因子:
4
作者:
Lefebvre, Veronique
通讯作者:
Lefebvre, Veronique