Specificity of emotion sequences in borderline personality disorder compared to posttraumatic stress disorder, bulimia nervosa, and healthy controls: an e-diary study.

Specificity of emotion sequences in borderline personality disorder compared to posttraumatic stress disorder, bulimia nervosa, and healthy controls: an e-diary study.
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DOI:
10.1186/s40479-017-0077-1
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发表时间:
2017
影响因子:
4.1
通讯作者:
Ebner-Priemer UW
Ebner-Priemer UW
中科院分区:
医学2区
文献类型:
--
作者:
Kockler TD;Tschacher W;Santangelo PS;Limberger MF;Ebner-Priemer UW

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与健康对照(HC)相比,边缘型人格障碍(BPD)患者在日常生活中表现出失调的情绪序列。目前缺乏关于这些发现的特异性的经验证据。为了在BPD患者中复制失调的情绪序列并研究这些序列的特异性,我们使用了43名女性BPD患者、28名创伤后应激障碍(PTSD)患者、20名神经性贪食症(BN)患者和28名HC患者的电子日记。为了捕捉情绪的快速动态,我们在24小时内每隔15分钟提示参与者评估他们当前的感知情绪。我们在情绪序列的激活、持续、转换和下调方面分析了组间差异。通过比较BPD患者和HC患者,我们复制了先前报道的7个情绪失调序列中的5个,以及113个未改变序列中的111个。然而,先前报道的情绪失调序列都没有表现出特异性,即与PTSD组或BN组相比,没有一个显示出更高的频率。除了这些发现之外,我们还揭示了BN患者的一个特殊发现,因为他们最频繁地从愤怒转变为厌恶。复制先前发现的失调和未改变的情绪序列加强了情绪序列的重要性。然而,缺乏特异性表明情绪序列是一种跨诊断特征。
Patients with borderline personality disorder (BPD) exhibit dysregulated emotion sequences in daily life compared to healthy controls (HC). Empirical evidence regarding the specificity of these findings is currently lacking. To replicate dysregulated emotion sequences in patients with BPD and to investigate the specificity of the sequences, we used e-diaries of 43 female patients with BPD, 28 patients with posttraumatic stress disorder (PTSD), 20 patients with bulimia nervosa (BN), and 28 HC. To capture the rapid dynamics of emotions, we prompted participants every 15 min over a 24-h period to assess their current perceived emotions. We analyzed group differences in terms of activation, persistence, switches, and down-regulation of emotion sequences. By comparing patients with BPD to HC, we replicated five of the seven previously reported dysregulated emotion sequences, as well as 111 out of 113 unaltered sequences. However, none of the previously reported dysregulated emotion sequences exhibited specificity, i.e., none revealed higher frequencies compared to the PTSD group or the BN group. Beyond these findings, we revealed a specific finding for patients with BN, as they most frequently switched from anger to disgust. Replicating previously found dysregulated and unaltered emotional sequences strengthens the significance of emotion sequences. However, the lack of specificity points to emotion sequences as transdiagnostic features.
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