Comparison of Various Obesity-Related Indices for Identification of Metabolic Syndrome: A Population-Based Study from Taiwan Biobank.
Comparison of Various Obesity-Related Indices for Identification of Metabolic Syndrome: A Population-Based Study from Taiwan Biobank.
复制标题
DOI：
10.3390/diagnostics10121081
复制
发表时间：
2020-12-12
期刊：
影响因子：
--
通讯作者：
Chen SC
中科院分区：
文献类型：
--
作者：
Chiu TH;Huang YC;Chiu H;Wu PY;Chiou HC;Huang JC;Chen SC
本研究旨在评估11项肥胖相关指标，包括体重指数（BMI）、腰围、腰高比、腰臀比、体型指数、腹部容积指数、身体肥胖指数、身体圆度指数、圆锥指数、内脏肥胖指数（VAI）和甘油三酯葡萄糖（TyG）指数，在识别成人代谢综合征（MetS）中的性能。5000名参与者的信息来自台湾生物银行。Logistic回归分析确定代谢综合征与肥胖相关指标之间的关系及比值比（OR）。使用受试者工作特征（ROC）曲线和曲线下面积（AUC）比较指标识别MetS的预测性能。多变量校正的逻辑回归显示，MetS的OR在每个指标的四分位数中增加。ROC曲线分析显示TyG指数在男性（AUC = 0.850）和女性（AUC = 0.890）中具有最大的AUC。此外，VAI在30 - 50岁男性（AUC = 0.867）和女性（AUC = 0.925）中的AUC最大，而TyG指数在51 - 70岁男性（AUC = 0.849）和女性（AUC = 0.854）中的AUC最大。在所研究的肥胖相关指标中，TyG指数和VAI在识别成年人MetS方面表现出最好的性能。TyG指数和VAI可作为临床评价代谢综合征的相关指标。
This study aimed to evaluate the performance of 11 obesity-related indices, including body mass index (BMI), waist circumference, waist-to-height ratio, waist–hip ratio, a body shape index, abdominal volume index, body adiposity index, body roundness index, conicity index, visceral adiposity index (VAI), and triglyceride glucose (TyG) index, in identifying metabolic syndrome (MetS) in adults. The information of 5000 participants was obtained from the Taiwan Biobank. Logistic regression analyses were performed to determine the associations between MetS and obesity-related indices with odds ratio (ORs). The predictive performance of the indices to identify MetS was compared using receiver operating characteristic (ROC) curves and areas under curves (AUCs). Multivariate-adjusted logistic regression showed that the ORs for MetS increased across the quartiles of each index. ROC curves analysis demonstrated that TyG index had the greatest AUC in men (AUC = 0.850) and women (AUC = 0.890). Furthermore, VAI had the greatest AUC in men (AUC = 0.867) and women (AUC = 0.925) aged 30−50 years, while TyG index had the greatest AUC in men (AUC = 0.849) and women (AUC = 0.854) aged 51−70 years. Among the studied obesity-related indices, TyG index and VAI exhibited the best performance for identifying MetS in adults. TyG index and VAI may be the relevant indices to assess MetS in clinical practice.
登录
查看更多内容
影响因子：
5.2
作者：
Kwon H;Pessin JE
通讯作者：
Pessin JE
影响因子：
6.9
作者：
Bergman, Richard N.;Stefanovski, Darko;Buchanan, Thomas A.;Sumner, Anne E.;Reynolds, James C.;Sebring, Nancy G.;Xiang, Anny H.;Watanabe, Richard M.
通讯作者：
Watanabe, Richard M.
影响因子：
3.7
作者：
Fujita M;Sato Y;Nagashima K;Takahashi S;Hata A
通讯作者：
Hata A
影响因子：
3.7
作者：
Amato MC;Pizzolanti G;Torregrossa V;Misiano G;Milano S;Giordano C
通讯作者：
Giordano C
台湾生物库：使大数据时代成为可能的跨数据库融合。
影响因子：
9.2
作者：
Lin JC;Fan CT;Liao CC;Chen YS
通讯作者：
Chen YS