"Risk factors of birth asphyxia".
"Risk factors of birth asphyxia".
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DOI：
10.1186/s13052-014-0094-2
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发表时间：
2014-12-20
影响因子：
3.6
通讯作者：
Shahid N
中科院分区：
文献类型：
--
作者：
Aslam HM;Saleem S;Afzal R;Iqbal U;Saleem SM;Shaikh MW;Shahid N
出生窒息是对胎儿或新生儿的一种侮辱，由于呼吸失败或呼吸困难，导致各器官的氧气灌注减少。据世卫组织统计，每年有400万新生儿死于出生窒息。我们的目的是评估产前、产时和胎儿出生窒息的危险因素。这是一项回顾性病例对照研究，在陶氏卫生科学大学卡拉奇民用医院儿科病房（一、二、三）和妇科病房（一、二、三）的新生儿重症监护室进行。研究于2011年1月至2012年11月进行。诊断为出生窒息的新生儿被视为“病例”，而正常阴道分娩或剖宫产无异常的新生儿被视为“对照组”。注意到母亲和新生儿的人口统计数据，并向母亲询问有关可能的危险因素的问题。伦理问题由陶氏健康科学大学卡拉奇民用医院机构审查委员会确认。所有数据均通过SPSS 19进行录入和分析。在总共240名新生儿中，123名是“病例”，117名是“对照组”。“病例”组产妇平均年龄24.22±3.38岁，对照组产妇平均年龄24.30±4.04岁。重要的产前危险因素为产妇年龄20-25岁（OR 0.30 CI 95% 0.07-1.21）、分娩状态（OR 0.20 CI 95% 0.11-0.37）、先兆子痫（OR 0.94 CI 95% 0.90-0.98）和原始性（OR 2.64 CI 95% 1.56-4.46）。重要的产时危险因素为臀位（OR 2.96 CI95% 1.25-7.02）、家中分娩（OR 16.16 CI95% 3.74-69.75）和产妇发热（OR 10.01 CI95% 3.78-26.52）。胎儿复苏（OR 23 CI 95% 31.27 ~ 1720.74）、早产儿（OR 0.34 CI 95% 0.19 ~ 0.58）、胎儿窘迫（OR 0.01 CI 95% 0.00 ~ 0.11）和婴儿体重（OR 0.13 CI 95% 0.05 ~ 0.32）是显著的胎儿危险因素。应采取措施防止新生儿死亡，重点是熟练的接生护理和对早产儿和低出生体重新生儿的适当护理。
Birth asphyxia is an insult to the fetus or newborn due to failure to breath or breathing poorly, leads to decrease oxygen perfusion to various organs. According to WHO, 4 million neonatal deaths occurred each year due to birth asphyxia. Our goal was to evaluate antepartum, intrapartum, and fetal risk factors of birth asphyxia. It was a Retrospective Case control study, conducted at Neonatal Intensive Care Unit of pediatric ward (I, II, III) and in Gynecology wards (I, II, III) of Civil Hospital Karachi, Dow University of Health Sciences. Study was conducted from January 2011-November 2012. Neonates diagnosed with birth asphyxia were considered as “cases” while neonates born either with normal vaginal delivery or by cesarean section having no abnormality were considered as “control”. Demographics of both the mother and neonate were noted and Questions regarding possible risk factors were asked from mother. Ethical issues were confirmed from Institutional review board of Civil Hospital Karachi, Dow University of Health Sciences. All data was entered and analyzed through SPSS 19. Out of total 240 neonates, 123 were “cases” and 117 were “control”. Mean maternal age in “case” group was 24.22 ± 3.38 while maternal age of control group was 24.30 ± 4.04. Significant antepartum risk factors were maternal age of 20–25 (OR 0.30 CI 95% 0.07-1.21), booking status (OR 0.20 CI 95% 0.11-0.37), pre-eclampsia (OR 0.94 CI 95% 0.90-0.98) and primigravidity (OR 2.64 CI 95% 1.56-4.46). Significant Intrapartum risk factors were breech presentation (OR 2.96 CI 95% 1.25-7.02), home delivery (OR 16.16 CI 95% 3.74-69.75) and maternal fever (OR 10.01 CI95% 3.78-26.52). Significant Fetal risk factors were resuscitation of child (OR 23 CI 95% 31.27-1720.74), pre-term babies(OR 0.34 CI 95% 0.19-0.58), fetal distress (OR 0.01 CI 95% 0.00-0.11) and baby weight (OR 0.13 CI 95% 0.05-0.32). Measures should be taken to prevent neonatal mortality with great emphasis on skilled attendance at birth and appropriate care of preterm and low birth weight neonates.
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