Quantitative and Chemical Fingerprint Analysis for the Quality Evaluation of Platycodi Radix Collected from Various Regions in China by HPLC Coupled with Chemometrics.
Quantitative and Chemical Fingerprint Analysis for the Quality Evaluation of Platycodi Radix Collected from Various Regions in China by HPLC Coupled with Chemometrics.
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DOI：
10.3390/molecules23071823
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发表时间：
2018-07-23
期刊：
影响因子：
--
通讯作者：
Gui S
中科院分区：
文献类型：
--
作者：
Lu H;Ju M;Chu S;Xu T;Huang Y;Chan Q;Peng H;Gui S
Platycodi Radix (PR) is the root of Platycodon grandiflorum (Jacq.) A. DC., which has been used for a long time in China to treat pulmonary diseases. The present study aimed to evaluate the quality of PR samples collected from 23 regions of 11 provinces in China. Eight saponins were quantified using HPLC coupled with evaporative light scattering detection (HPLC-ELSD). The samples with the highest total contents of saponins were from southern China, such as Yunnan, Guangxi, Jiangxi, and Guangzhou. The fingerprint analysis of PR samples was conducted by HPLC-UV method. Nineteen common peaks were selected and the similarity values varied from 0.607 to 0.921. These findings indicated that the saponins contents of PR from different regions varied significantly, with PR samples from southern China having the highest contents of saponins. These comprehensive methods were successful in evaluating the quality of PR samples from northern and southern China, which will serve as a guide for the development of PR as a clinical medication.
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影响因子：
--
作者：
Nyakudya E;Jeong JH;Lee NK;Jeong YS
通讯作者：
Jeong YS
DOI：
10.3390/molecules22112037
发表时间：
2017-11-22
期刊：
Molecules (Basel, Switzerland)
影响因子：
--
作者：
Wang CK;Shih LY;Chang KY
通讯作者：
Chang KY
影响因子：
5.4
作者：
Jang, Kyung-Jun;Kim, Hong Ki;Choi, Yung Hyun
通讯作者：
Choi, Yung Hyun
影响因子：
5.6
作者：
Liu Z;Wang D;Li D;Zhang S
通讯作者：
Zhang S
影响因子：
2.7
作者：
Chun, Jaemoo;Ha, In Jin;Kim, Yeong Shik
通讯作者：
Kim, Yeong Shik