Cardiac Performance and Cardiopulmonary Fitness After Infection With SARS-CoV-2.
Cardiac Performance and Cardiopulmonary Fitness After Infection With SARS-CoV-2.
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DOI：
10.3389/fcvm.2022.871603
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发表时间：
2022
影响因子：
3.6
通讯作者：
Kim, Won Yong
中科院分区：
文献类型：
--
作者：
Wood, Gregory;Kirkevang, Therese Stegeager;Agergaard, Jane;Leth, Steffen;Hansen, Esben Sovso Szocska;Laustsen, Christoffer;Larsen, Anders Hostrup;Jensen, Henrik Kjaerulf;Ostergaard, Lars Jorgen;Botker, Hans Erik;Poulsen, Steen Hvitfeldt;Kim, Won Yong
COVID-19 后，持续性心脏症状是一种越来越多的报道现象。然而，心脏症状的根本原因尚不清楚。本研究旨在确定急性 COVID-19 感染 1 年后这些症状的根本原因（如果有）。使用超声心动图、心血管磁共振 (CMR)、6 分钟步行测试、心肺运动测试和心电图对 22 名患有持续心脏症状的个体进行了前瞻性调查。从诊断出 COVID-19 到进行调查，中位数为 382 天 (IQR 368, 442)。作为一个队列，他们的超声心动图、CMR、6 分钟步行测试和运动测试结果均在正常范围内。与健康对照组相比，超声心动图测量的左心室射血分数（61.45±6.59％）、整体纵向应变（19.80±3.12％）或三尖瓣环平面收缩期偏移（24.96±5.55mm）没有差异。最大摄氧量 (2045.00 ± 658.40 ml/min)、最大摄氧量百分比 (114.80 ± 23.08 %) 和 6 分钟步行距离 (608.90 ± 54.51 m) 超出了患者队列的预期，而肌钙蛋白 I (5.59 ± 6.59 ng/l) 和 Nt-proBNP (88.18 ± 54.27 纳克/升）正常。在 22 名自我报告有持续性心脏症状的患者队列中，我们发现在 COVID-19 一年后没有潜在的心脏病或心肺健康状况下降。
Persistent cardiac symptoms are an increasingly reported phenomenon following COVID-19. However, the underlying cause of cardiac symptoms is unknown. This study aimed to identify the underlying causes, if any, of these symptoms 1 year following acute COVID-19 infection. 22 individuals with persistent cardiac symptoms were prospectively investigated using echocardiography, cardiovascular magnetic resonance (CMR), 6-min walking test, cardio-pulmonary exercise testing and electrocardiography. A median of 382 days (IQR 368, 442) passed between diagnosis of COVID-19 and investigation. As a cohort their echocardiography, CMR, 6-min walking test and exercise testing results were within the normal ranges. There were no differences in left ventricular ejection fraction (61.45 ± 6.59 %), global longitudinal strain (19.80 ± 3.12 %) or tricuspid annular plane systolic excursion (24.96 ± 5.55 mm) as measured by echocardiography compared to a healthy control group. VO2 max (2045.00 ± 658.40 ml/min), % expected VO2 max (114.80 ± 23.08 %) and 6-minute distance walked (608.90 ± 54.51 m) exceeded that expected for the patient cohort, whilst Troponin I (5.59 ± 6.59 ng/l) and Nt-proBNP (88.18 ± 54.27 ng/l) were normal. Among a cohort of 22 patients with self-reported persistent cardiac symptoms, we identified no underlying cardiac disease or reduced cardiopulmonary fitness 1 year following COVID-19.
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DOI：
10.1183/16000617.0101-2018
发表时间：
2019-12-31
期刊：
European respiratory review : an official journal of the European Respiratory Society
影响因子：
--
作者：
Radtke, Thomas;Crook, Sarah;Hebestreit, Helge
通讯作者：
Hebestreit, Helge
影响因子：
4.2
作者：
Leth S;Gunst JD;Mathiasen V;Hansen K;Søgaard O;Østergaard L;Jensen-Fangel S;Storgaard M;Agergaard J
通讯作者：
Agergaard J
影响因子：
6.2
作者：
Lang, Roberto M.;Badano, Luigi P.;Voigt, Jens-Uwe
通讯作者：
Voigt, Jens-Uwe
DOI：
10.1016/j.echo.2018.06.010
发表时间：
2018-10-01
影响因子：
6.5
作者：
Larsen, Anders Hostrup;Clemmensen, Tor Skibsted;Poulsen, Steen Hvitfeldt
通讯作者：
Poulsen, Steen Hvitfeldt
影响因子：
24
作者：
Puntmann, Valentina O.;Carerj, M. Ludovica;Nagel, Eike
通讯作者：
Nagel, Eike