Sarcopenia in chronic obstructive pulmonary disease: A study of prevalence and associated factors in the Southeast Asian population.
Sarcopenia in chronic obstructive pulmonary disease: A study of prevalence and associated factors in the Southeast Asian population.
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DOI：
10.1177/1479972317743759
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发表时间：
2018-08
影响因子：
4.1
通讯作者：
Sawanyawisuth K
中科院分区：
文献类型：
--
作者：
Limpawattana P;Inthasuwan P;Putraveephong S;Boonsawat W;Theerakulpisut D;Sawanyawisuth K
慢性阻塞性肺疾病（COPD）被描述为一种全身性疾病。肌肉减少症是与几种不良结局相关的全身效应之一。本研究的目的是估计东南亚COPD患者中肌肉减少症的患病率，并确定与肌肉减少症相关的因素。这是一项针对2015年5月至2016年12月在COPD诊所就诊的COPD患者的横断面研究。收集基线特征，并使用双能X线吸收法测量骨骼肌质量。使用握力评估肌肉力量，并使用6分钟步行距离作为身体表现的测量。招募了121名参与者。其中大多数是男性（92.6%）。肌肉减少症的患病率为24%（29例）。与肌肉减少症相关的独立因素为年龄≥ 75岁（校正比值比（AOR）13.3）、COPD严重程度（中度和重度COPD的AOR分别为19.2和13.4）、改良医学研究理事会（MMRC）量表（AOD 1.9）和肥胖（AOR 0.04）。肌肉减少症影响约四分之一的COPD患者。年龄、COPD严重程度、MMRC量表和BMI状态是肌肉减少症的相关因素。
Chronic obstructive pulmonary disease (COPD) has been described as a systemic disease. Sarcopenia is one of the systemic effects that is related to several adverse outcomes. The objectives of this study were to estimate the prevalence of sarcopenia and to determine the factors associated with sarcopenia in COPD patients in Southeast Asia. This was a cross-sectional study of COPD patients who attended a COPD clinic from May 2015 to December 2016. Baseline characteristics were collected and dual-energy X-ray absorptiometry was used to measure skeletal muscle mass. Handgrip strength was used to assess muscle strength, and as a measurement of physical performance, the 6-min walk distance was used. One hundred and twenty-one participants were recruited. Most of them were men (92.6%). Prevalence of sarcopenia was 24% (29 cases). Independent factors associated with sarcopenia were age ≥ 75 years (adjusted odds ratio (AOR) 13.3, severity of COPD (AOR 19.2 and 13.4 for moderate and severe COPD), Modified Medical Research Council (MMRC) scale (AOD 1.9), and obesity (AOR 0.04). Sarcopenia affects about one-quarter of COPD patients. Age, severity of COPD, MMRC scale, and BMI status were the factors associated with sarcopenia.
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影响因子：
--
作者：
Kim TN;Choi KM
通讯作者：
Choi KM
影响因子：
9.6
作者：
Ischaki, Eleni;Papatheodorou, Georgios;Loukides, Stelios
通讯作者：
Loukides, Stelios
DOI：
10.1590/s1806-37132015000000040
发表时间：
2015-09
期刊：
Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
影响因子：
--
作者：
Costa TM;Costa FM;Moreira CA;Rabelo LM;Boguszewski CL;Borba VZ
通讯作者：
Borba VZ
影响因子：
3.6
作者：
Lerario, M. C.;Sachs, A.;Jardim, J. R.
通讯作者：
Jardim, J. R.
影响因子：
6.7
作者：
Cesari, Matteo;Pedone, Claudio;Incalzi, Raffaele Antonelli
通讯作者：
Incalzi, Raffaele Antonelli