Large thigh circumference is associated with lower blood pressure in overweight and obese individuals: a community-based study

Large thigh circumference is associated with lower blood pressure in overweight and obese individuals: a community-based study
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大腿围大与超重和肥胖者的血压降低有关:一项基于社区的研究

DOI:
10.1530/ec-19-0539
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发表时间:
2020-03
影响因子:
2.9
通讯作者:
Qing Su
Qing Su
中科院分区:
医学3区
文献类型:
--
作者:
Jie Shi;Zhen Yang;Yixin Niu;Ning Lin;Xiaoyong Li;Hongmei Zhang;Hongxia Gu;Jie Wen;Guang Ning;Li Qin;Qing Su

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目的 大腿围较小与糖尿病、心血管疾病和总死亡率的风险增加相关。本研究的目的是评估中老年人群大腿围与高血压的关系。方法 共有 9520 名 40 岁及以上测量过大腿围的个体进行分析。大腿围的测量是在大腿臀沟正下方进行的。在逻辑回归分析中测试了大腿围与高血压的关联,并报告为比值比 (OR),CI 为 95%。结果大腿围与收缩压、舒张压、空腹血糖、总胆固醇呈负相关。与大腿围最低三分位数组相比,最高三分位数组患高血压的风险显着降低,无论是超重个体(OR 0.68;95% CI 0.59–0.79,P < 0.001)还是肥胖个体(OR 0.51;95% CI 0.38–0.70,P< 0.001)。结论 在本研究中,大腿围大与超重和肥胖的中国人患高血压的风险较低相关。
Objective A small thigh circumference is associated with an increased risk of diabetes, cardiovascular diseases, and total mortality. The purpose of this study was to evaluate the association between thigh circumference and hypertension in the middle-aged and elderly population. Methods A total of 9520 individuals aged 40 years and older with measurement of thigh circumference were available for analysis. The measurement of thigh circumference was performed directly below the gluteal fold of the thigh. The association of thigh circumference with hypertension was tested in logistic regression analyses and reported as odds ratio (OR) with 95% CI. Results Thigh circumference was negatively correlated with systolic blood pressure, diastolic blood pressure, fasting glucose, and total cholesterol. Compared with the lowest thigh circumference tertile group, the risk of hypertension was significantly lower in the highest tertile group, both in overweight individuals (OR 0.68; 95% CI 0.59–0.79, P < 0.001) and obese individuals (OR 0.51; 95% CI 0.38–0.70, P < 0.001). Conclusion In the present study, large thigh circumference is associated with lower risk of hypertension in overweight and obese Chinese individuals.
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