Changes in pain catastrophizing predict later changes in fibromyalgia clinical and experimental pain report: cross-lagged panel analyses of dispositional and situational catastrophizing.
Changes in pain catastrophizing predict later changes in fibromyalgia clinical and experimental pain report: cross-lagged panel analyses of dispositional and situational catastrophizing.
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DOI：
10.1186/ar4073
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发表时间：
2012-10-25
影响因子：
4.9
通讯作者：
Fontaine KR
中科院分区：
文献类型：
--
作者：
Campbell CM;McCauley L;Bounds SC;Mathur VA;Conn L;Simango M;Edwards RR;Fontaine KR
纤维肌痛 (FM) 的特点是广泛的弥漫性疼痛和感觉异常，与无痛样本和慢性疼痛样本相比，与痛苦和与疼痛相关的灾难化指数升高相关。灾难化是一种普遍存在的负面心理状态，并且是负面疼痛相关结果（例如临床疼痛强度和身体残疾）的有力预测因素。在实验引起的疼痛的背景下测量的情景灾难化与疼痛敏感性增强密切相关，这是纤维肌痛病理生理学的核心方面。然而，人们对灾难性和疼痛相关“结果”之间关联的时间过程知之甚少。大多数研究仅涉及单个时间点的疼痛和灾难化的静态评估，这对观察到的关联的方向提供了很少的洞察。我们试图在一项更大的随机对照纵向试验中研究灾难化与临床疼痛（子研究 1）和实验诱发的疼痛（子研究 2）指数之间的时间关系。 57 名 FM 患者在生活方式体育活动研究期间完成了灾难性、抑郁和疼痛问卷，以及基线、干预后和三个月随访的实验室冷加压疼痛测试。使用交叉滞后面板分析来解决这些时间关系。在子研究 1 中，分析显示，倾向性灾难化评级的前后变化前瞻性地解释了随后的临床疼痛评级随访后变化的独特方差（p = 0.005），而疼痛评级前后的变化并不能解释灾难化评级的随访后变化的独特方差。在子研究 2 中通过实验观察到了相同的模式，情景灾难化评级的前后变化前瞻性地解释了实验疼痛评级后续随访后变化的独特方差（p = 0.014），而疼痛评级前后变化并没有解释灾难化评级随访后变化的独特方差。具体来说，灾难化的最初改变与临床和实验引起的疼痛的后续改变相关。控制抑郁水平并不会影响结果。这些发现提供了经验证据，表明灾难性过程可能先于并导致 FM 患者疼痛经历的后续改变。临床试验.gov：NCT00383084。
Fibromyalgia (FM), characterized by wide-spread diffuse pain and sensory abnormalities, is associated with elevated indices of distress and pain-related catastrophizing compared to both pain-free samples and those with chronic pain conditions. Catastrophizing is a pervasive negative mental set, and is a strong predictor of negative pain-related outcomes such as clinical pain intensity, and physical disability. Situational catastrophizing, measured in the context of experimentally-induced pain, is strongly related to enhanced pain sensitivity, a core aspect of the pathophysiology of fibromyalgia. However, little is known regarding the temporal course of the association between catastrophizing and pain-related "outcomes". Most studies involve only static assessments of pain and catastrophizing at a single time point, which provides little insight into the direction of the observed associations. We sought to investigate the temporal relationships between catastrophizing and indices of both clinical pain (substudy 1) and experimentally-induced pain (substudy 2) in a larger randomized controlled longitudinal trial. Fifty-seven patients with FM completed catastrophizing, depression, and pain questionnaires as well as laboratory cold pressor pain testing at baseline, post-intervention and three month follow-up during a lifestyle physical activity study. Cross-lagged panel analyses were used to address these temporal relationships. In substudy 1, analyses revealed that pre-to-post changes in dispositional catastrophizing ratings prospectively accounted for unique variance in subsequent post-to-follow-up changes in clinical pain ratings (p = 0.005), while pre-to-post changes in pain ratings did not account for unique variance in post-to-follow-up changes in catastrophizing ratings. An identical pattern was observed experimentally in substudy 2, with pre-to-post changes in situational catastrophizing ratings prospectively accounting for unique variance in subsequent post-to-follow-up changes in experimental pain ratings (p = 0.014), while pre-to-post changes in pain ratings did not account for unique variance in post-to-follow-up changes in catastrophizing ratings. Specifically, initial alterations in catastrophizing were associated with subsequent alterations in clinical and experimentally induced pain. Controlling for levels of depression did not affect the results. These findings provide empirical evidence that catastrophizing processes might precede and contribute to subsequent alterations in the pain experience for FM patients. clinicaltrials.gov: NCT00383084.
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DOI：
10.1097/rhu.0b013e31820e7ea7
发表时间：
2011-03
期刊：
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
影响因子：
--
作者：
Fontaine KR;Conn L;Clauw DJ
通讯作者：
Clauw DJ
DOI：
10.3205/psm000057
发表时间：
2009-04-29
期刊：
Psycho-social medicine
影响因子：
--
作者：
Leonhardt C;Lehr D;Chenot JF;Keller S;Luckmann J;Basler HD;Baum E;Donner-Banzhoff N;Pfingsten M;Hildebrandt J;Kochen MM;Becker A
通讯作者：
Becker A
影响因子：
3.1
作者：
Osman, A;Barrios, FX;Grittmann, L
通讯作者：
Grittmann, L
影响因子：
4.1
作者：
Burns, JW;Glenn, B;Lofland, K
通讯作者：
Lofland, K
影响因子：
7.4
作者：
Dixon, KE;Thorn, BE;Ward, LC
通讯作者：
Ward, LC