Model answers to lipid membrane questions.
Model answers to lipid membrane questions.
复制标题
脂质膜问题的模型答案。
DOI：
10.1101/cshperspect.a004622
复制
发表时间：
2011
影响因子：
7.2
通讯作者：
O. Mouritsen
中科院分区：
文献类型：
--
作者：
O. Mouritsen
自从发现生物膜具有脂质分子的双分子片的核心以来，脂质双层一直是研究生物膜的物理化学和功能性质的模型实验室。实验和理论模型帮助实验科学家计划实验和解释数据。理论模型是理论科学家在膜理论和实验之间建立联系的首选工具。最重要的是，模型有助于塑造我们的直觉，即哪些膜问题是更基本和相关的问题。在这里，我们回顾了一些膜模型的脂质自组装，单层，双层，脂质体和脂质-蛋白质相互作用，并说明这些模型可以帮助回答现代脂质细胞生物学中的问题。
Ever since it was discovered that biological membranes have a core of a bimolecular sheet of lipid molecules, lipid bilayers have been a model laboratory for investigating physicochemical and functional properties of biological membranes. Experimental and theoretical models help the experimental scientist to plan experiments and interpret data. Theoretical models are the theoretical scientist's preferred toys to make contact between membrane theory and experiments. Most importantly, models serve to shape our intuition about which membrane questions are the more fundamental and relevant ones to pursue. Here we review some membrane models for lipid self-assembly, monolayers, bilayers, liposomes, and lipid-protein interactions and illustrate how such models can help answering questions in modern lipid cell biology.
DOI：
10.1016/j.bbalip.2008.09.002
发表时间：
2008-11
影响因子：
4.8
作者：
Goni, Felix M.;Alonso, Alicia;Bagatolli, Luis A.;Brown, Rhoderick E.;Marsh, Derek;Prieto, Manuel;Thewalt, Jenifer L.
通讯作者：
Thewalt, Jenifer L.
影响因子：
3.4
作者：
Veatch, SL;Keller, SL
通讯作者：
Keller, SL
影响因子：
3.4
作者：
Veatch, SL;Polozov, IV;Keller, SL
通讯作者：
Keller, SL