Volumetric multishot echo‐planar spectroscopic imaging
Volumetric multishot echo‐planar spectroscopic imaging
复制标题
体积多次发射回波平面光谱成像
DOI：
10.1002/mrm.1182
复制
发表时间：
2001
影响因子：
3.3
通讯作者：
A. Mamelak
中科院分区：
文献类型：
--
作者：
J. Tyszka;A. Mamelak
快速容积磁共振波谱成像（MRSI）在肿瘤、癫痫等局灶性脑疾病的诊断和治疗中具有重要意义。描述了一种体积多激发回波平面光谱成像（MEPSI）策略，该策略允许在大约20分钟内绘制全脑代谢物图谱。在空间和时间域中使用多激发轨迹，可以减少每个回波串期间的累积相位，并耐受传统的傅里叶重建而无需重新网格化。还描述了对由时域的多激发采集引起的相位不连续性的广义校正，其独立于空间k空间轨迹，因此也适用于多激发螺旋MRSI。从5名正常受试者中获取全脑、脂质抑制的MEPSI数据。所有受试者的N-乙酰天冬氨酸（NAA）、胆碱（Cho）和肌酸（Cr）标测图的平均信噪比（SNR）（±SE）分别为21.3 ± 1.8、11.7 ± 0.6和9.2 ± 0.6，计算的体素大小为2.33 ml。Magn Reson Med 46：219-227，2001。© 2001 Wiley利斯公司
Rapid volumetric magnetic resonance spectroscopic imaging (MRSI) is potentially of great relevance to the diagnosis and treatment of focal cerebral diseases such as cancer and epilepsy. A strategy for volumetric multishot echo‐planar spectroscopic imaging (MEPSI) is described which allows whole‐brain metabolite mapping in approximately 20 min. A multishot trajectory is used in both the spatial and temporal domains which reduces the accumulated phase during each echo train and tolerates conventional Fourier reconstruction without regridding. Also described is a generalized correction for phase discontinuities arising from the multishot acquisition of the time domain, which is independent of the spatial k‐space trajectory and is therefore also applicable to multishot spiral MRSI. Whole‐brain, lipid‐suppressed MEPSI data were acquired from five normal subjects. The mean signal‐to‐noise ratios (SNRs) (±SE) for the n‐acetylaspartate (NAA), choline (Cho), and creatine (Cr) maps across all subjects were 21.3 ± 1.8, 11.7 ± 0.6, and 9.2 ± 0.6, respectively, with a computed voxel size of 2.33 ml. Magn Reson Med 46:219–227, 2001. © 2001 Wiley‐Liss, Inc.
影响因子：
19.7
作者：
J. Kurhanewicz;Daniel B. Vigneron;Hedvig Hricak;Farhad Parivar;S. Nelson;K. Shinohara;P. Carroll
通讯作者：
J. Kurhanewicz;Daniel B. Vigneron;Hedvig Hricak;Farhad Parivar;S. Nelson;K. Shinohara;P. Carroll
影响因子：
19.7
作者：
Kurhanewicz, J;Vigneron, DB;Nelson, SJ
通讯作者：
Nelson, SJ