Multiple Pancreatic Masses Associated With Autoimmunity
Multiple Pancreatic Masses Associated With Autoimmunity
复制标题
与自身免疫相关的多发性胰腺肿块
DOI：
--
复制
发表时间：
1998
影响因子：
9.8
通讯作者：
Y. Kobashi
中科院分区：
文献类型：
--
作者：
M. Ohana;K. Okazaki;K. Hajiro;Y. Kobashi
59岁女性，血清γ -球蛋白滴度高，抗核抗体阳性，胰腺多发肿块。在1年的病程中，Sjögren综合征出现，胰腺肿块弥漫性扩散并压迫主胰管。腹部胰腺活检显示许多CD4阳性t淋巴细胞浸润到导管和表达HLA-DR抗原的腺泡细胞。提示诊断为自身免疫性胰腺炎。经口服强的松龙治疗，上述异常症状有明显改善。在本报告中，提出了一例自身免疫相关的多发性胰腺肿块与Sjögren综合征，并讨论了可能的机制。
A 59-year-old woman was detected to have a high titer of serum gamma-globulin, positive antinuclear antibody and multiple pancreatic masses. In the course of 1 yr, Sjögren's syndrome developed, and her pancreatic masses spread diffusely and compressed the main pancreatic duct. A pancreatic biopsy by an exploration of the abdomen showed that many CD4 positive T-lymphocytes had infiltrated to the ducts and acinar cells expressing HLA-DR antigens. This suggested a diagnosis of autoimmune-related pancreatitis. She was treated with oral prednisolone, and a marked improvement of the above abnormal findings followed. In this report, a case of autoimmune-related multiple pancreatic masses associated with Sjögren's syndrome is presented, and a possible mechanism is discussed.
自身免疫性甲状腺疾病和甲状腺细胞 II 类主要组织相容性复合体抗原。
影响因子：
3.2
作者：
Piccinini,LA;Roman,SH;Davies,TF
通讯作者：
Davies,TF