Signaling Organogenesis in Parasitic Angiosperms: Xenognosin Generation, Perception, and Response
Signaling Organogenesis in Parasitic Angiosperms: Xenognosin Generation, Perception, and Response
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寄生被子植物的信号器官发生：异种素的产生、感知和反应
DOI：
--
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发表时间：
2000
影响因子：
4.8
通讯作者：
David G. Lynn
中科院分区：
文献类型：
--
作者：
W. Keyes;Ronan C. O’Malley;Dongjin Kim;David G. Lynn
被子植物中的寄生策略通常通过将发育转变与宿主识别信号紧密耦合在一个被称为异知的过程中而成功。在玄参科中，独脚金是研究最多和最好理解的寄生成员就主机识别的过程。特异性的外源蛋白调节种子萌发、寄主附着器官、吸器的发育以及寄主-寄生物整合的几个后期阶段。在这里，我们讨论的信号调节吸器的发展，关键营养/寄生在这个专性寄生虫的生命周期中的过渡。我们提供的证据，本地化生产的H2 O2在独脚金根尖，并建议如何使用这种氧化剂利用宿主过氧化物酶和细胞壁果胶产生一个简单的苯醌信号。这种苯醌异染素被证明是培养幼苗吸器诱导的必要和充分条件。此外，提供的证据表明，苯醌结合到氧化还原活性位点完成了“氧化还原回路”，以介导信号感知。这种氧化还原反应调节特定标记基因的时间依赖性表达，这些基因对于成熟宿主附着器官的发育至关重要。这些研究扩展了寄生植物内器官发生的分子调控所需的一系列事件，并提出了可能在高等植物中常见的新的信号特征和分子机制。
A bstractParasitic strategies within the angiosperms generally succeed by tightly coupling developmental transitions with host recognition signals in a process referred to as xenognosis. Within the Scrophulariaceae, Striga asiatica is among the most studied and best understood parasitic member with respect to the processes of host recognition. Specific xenognosins regulate seed germination, the development of the host attachment organ, the haustorium, and several later stages of host-parasite integration. Here we discuss the signals regulating the development of the haustorium, the critical vegetative/parasitic transition in the life cycle of this obligate parasite. We provide evidence for the localized production of H2O2 at the Striga root tip and suggest how this oxidant is used to exploit host peroxidases and cell wall pectins to generate a simple benzoquinone signal. This benzoquinone xenognosin proves to be both necessary and sufficient for haustorial induction in cultured seedlings. Furthermore, evidence is provided that benzoquinone binding to a redox active site completes a ``redox circuit'' to mediate signal perception. This redox reaction regulates the time-dependent expression of specific marker genes critical for the development of the mature host attachment organ. These studies extend the emerging series of events necessary for the molecular regulation of organogenesis within the parasitic plants and suggest novel signaling features and molecular mechanisms that may be common across higher plants.
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影响因子：
56.9
作者：
STORZ, G;TARTAGLIA, LA;AMES, BN
通讯作者：
AMES, BN
百日咳毒素和霍乱毒素 ADP 核糖基化人中性粒细胞底物的亚细胞分布和膜关联。
DOI：
--
发表时间：
1989
期刊：
Journal of immunology (Baltimore, Md. : 1950)
影响因子：
--
作者：
Volpp,BD;Nauseef,WM;Clark,RA
通讯作者：
Clark,RA
影响因子：
56.9
作者：
KNAUS, UG;HEYWORTH, PG;BOKOCH, GM
通讯作者：
BOKOCH, GM
DOI：
10.1073/pnas.87.24.9943
发表时间：
1990-12-01
影响因子：
11.1
作者：
STAAL, FJT;ROEDERER, M;HERZENBERG, LA
通讯作者：
HERZENBERG, LA