Psychiatric profile and attention deficits in postural tachycardia syndrome.

Psychiatric profile and attention deficits in postural tachycardia syndrome.
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DOI:
10.1136/jnnp.2008.144360
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发表时间:
2009-03
期刊:
Journal of neurology, neurosurgery, and psychiatry
影响因子:
--
通讯作者:
Shelton RC
Shelton RC
中科院分区:
其他
文献类型:
--
作者:
Raj V;Haman KL;Raj SR;Byrne D;Blakely RD;Biaggioni I;Robertson D;Shelton RC

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体位性心动过速综合征(POTS)的患者通常表现出焦虑和注意力不集中。我们正式评估了POTS患者的精神障碍和注意力不集中,并将他们与注意力缺陷多动障碍(ADHD)患者和对照组进行了比较。POTS患者(N=21)、ADHD患者(N=18)和正常对照组(N=20)接受了DSM-IV精神障碍的评估,并完成了一系列问卷,评估了抑郁、焦虑和ADHD的特征。与普通人群相比,POTS患者的严重抑郁症或焦虑症(包括恐慌症)的患病率没有增加。患有POTS的患者有轻度抑郁。他们在贝克焦虑量表上的得分为中度焦虑,但并未表现出高度的焦虑敏感性。POTS患者在注意力不集中和ADHD分量表上的得分显著高于对照组。这些症状在儿童时期是不存在的。患有POTS的患者一生中精神障碍的患病率不会增加。尽管他们可能看起来很焦虑,但他们并没有过度的认知焦虑。他们确实经历了严重的注意力不集中,这可能是残疾的一个重要来源。
Patients with postural tachycardia syndrome (POTS) often appear anxious and report inattention. We formally assessed patients with POTS for psychiatric disorders and inattention and compared them to patients with attention deficit hyperactivity disorder (ADHD) and control subjects. Patients with POTS (N=21), ADHD (N=18) and normal control subjects (N=20) were assessed for DSM-IV psychiatric disorders and completed a battery of questionnaires that assessed depression, anxiety and ADHD characteristics. Patients with POTS did not have an increased prevalence of major depression or anxiety disorders, including panic disorder, compared to the general population. Patients with POTS had mild depression. They scored as moderately anxious on the Beck Anxiety Inventory, but did not exhibit a high level of anxiety sensitivity. Patients with POTS scored significantly higher on inattention and ADHD subscales than control subjects. These symptoms were not present during childhood. Patients with POTS do not have an increased lifetime prevalence of psychiatric disorders. Although they may seem anxious, they do not have excess cognitive anxiety. They do experience significant inattention, which may be an important source of disability.
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