How much does the amphioxus genome represent the ancestor of chordates?
How much does the amphioxus genome represent the ancestor of chordates?
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DOI:
10.1093/bfgp/els003
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发表时间:
2012-03
影响因子:
4
通讯作者:
Robinson-Rechavi M
中科院分区:
文献类型:
--
作者:
Louis A;Roest Crollius H;Robinson-Rechavi M
One of the main motivations to study amphioxus is its potential for understanding the last common ancestor of chordates, which notably gave rise to the vertebrates. An important feature in this respect is the slow evolutionary rate that seems to have characterized the cephalochordate lineage, making amphioxus an interesting proxy for the chordate ancestor, as well as a key lineage to include in comparative studies. Whereas slow evolution was first noticed at the phenotypic level, it has also been described at the genomic level. Here, we examine whether the amphioxus genome is indeed a good proxy for the genome of the chordate ancestor, with a focus on protein-coding genes. We investigate genome features, such as synteny, gene duplication and gene loss, and contrast the amphioxus genome with those of other deuterostomes that are used in comparative studies, such as Ciona, Oikopleura and urchin.
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影响因子:
9.8
作者:
Woolfe A;Goodson M;Goode DK;Snell P;McEwen GK;Vavouri T;Smith SF;North P;Callaway H;Kelly K;Walter K;Abnizova I;Gilks W;Edwards YJ;Cooke JE;Elgar G
通讯作者:
Elgar G
影响因子:
2.9
作者:
Castro, LFC;Hoiianda, PWH
通讯作者:
Hoiianda, PWH
影响因子:
10.7
作者:
Brunet, Frederic G.;Roest Crollius, Hugues;Robinson-Rechavi, Marc
通讯作者:
Robinson-Rechavi, Marc
影响因子:
2.7
作者:
Castro, L. Filipe C.;Rasmussen, Stacy L. K.;Holland, Linda Z.
通讯作者:
Holland, Linda Z.
影响因子:
3.5
作者:
Minguillón, C;Ferrier, DEK;Garcia-Fernàndez, J
通讯作者:
Garcia-Fernàndez, J