Hypothesis on the possible relevance of the immunogenic cell death in the treatment of gestational trophoblastic neoplasms.
Hypothesis on the possible relevance of the immunogenic cell death in the treatment of gestational trophoblastic neoplasms.
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DOI:
10.1016/j.tranon.2021.101224
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发表时间:
2021-12
影响因子:
5
通讯作者:
Brandi G
中科院分区:
文献类型:
--
作者:
Frega G;Kepp O;Turchetti D;Rizzo A;Pantaleo MA;Brandi G
The genetic background and the antigenic landscape of cancer cells play a critical role in the response to immunotherapies. A high tumor antigenicity, together with an increased adjuvanticity potentially induced by a peculiar type of cell death, namely immunogenic cell death (ICD), could foster the response to immunogenic therapies. The gestational trophoblastic neoplasm (GTN) is a one-of-a-kind cancer in the oncological landscape due to its exclusive genomic makeup. The prognosis of GTN is significantly better than non-gestational trophoblastic neoplasm (nGTN). Due to its peculiar genetic inheritance, GTN potentially constitutes a singular archetype in the immuno-oncological field.
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影响因子:
4
作者:
Jia N;Chen Y;Tao X;Ou E;Lu X;Feng W
通讯作者:
Feng W
影响因子:
7.3
作者:
Garg AD;Galluzzi L;Apetoh L;Baert T;Birge RB;Bravo-San Pedro JM;Breckpot K;Brough D;Chaurio R;Cirone M;Coosemans A;Coulie PG;De Ruysscher D;Dini L;de Witte P;Dudek-Peric AM;Faggioni A;Fucikova J;Gaipl US;Golab J;Gougeon ML;Hamblin MR;Hemminki A;Herrmann M;Hodge JW;Kepp O;Kroemer G;Krysko DV;Land WG;Madeo F;Manfredi AA;Mattarollo SR;Maueroder C;Merendino N;Multhoff G;Pabst T;Ricci JE;Riganti C;Romano E;Rufo N;Smyth MJ;Sonnemann J;Spisek R;Stagg J;Vacchelli E;Vandenabeele P;Vandenberk L;Van den Eynde BJ;Van Gool S;Velotti F;Zitvogel L;Agostinis P
通讯作者:
Agostinis P
影响因子:
11.1
作者:
Humeau, Juliette;Sauvat, Allan;Kroemer, Guido
通讯作者:
Kroemer, Guido
影响因子:
45.3
作者:
Alifrangis, Constantine;Agarwal, Roshan;Seckl, Michael J.
通讯作者:
Seckl, Michael J.
DOI:
10.1007/s12094-017-1793-0
发表时间:
2018-01
期刊:
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
影响因子:
--
作者:
Santaballa A;García Y;Herrero A;Laínez N;Fuentes J;De Juan A;Rodriguez Freixinós V;Aparicio J;Casado A;García-Martinez E
通讯作者:
García-Martinez E