DBMLoc: a Database of proteins with multiple subcellular localizations.

DBMLoc: a Database of proteins with multiple subcellular localizations.
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DBMLoc:具有多个亚细胞定位的蛋白质数据库。

DOI:
10.1186/1471-2105-9-127
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发表时间:
2008-02-28
期刊:
影响因子:
3
通讯作者:
Sun Z
Sun Z
中科院分区:
生物学4区
文献类型:
--
作者:
Zhang S;Xia X;Shen J;Zhou Y;Sun Z

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亚细胞定位信息是蛋白质功能研究的关键特征之一。定位于特定的亚细胞区室对于蛋白质有效地发挥功能是必不可少的。具有多个定位的蛋白质将提供更多的线索。这类蛋白质可能占很高的比例,甚至超过35%。我们已经开发了一个具有多个亚细胞定位的蛋白质数据库,命名为DBMLoc。初始版本包含10470多个亚细胞定位注释条目。注释是从主要的蛋白质数据库、特定的亚细胞定位数据库和文献文本中收集的。所有蛋白质条目都与GO注释和SwissProt交叉引用。蛋白质-蛋白质相互作用也被注释。它们被分为12个大的亚细胞定位类别的基础上GO层次结构和原始注释。下载,搜索和序列BLAST工具也可在网站上。DBMLoc是一个蛋白质数据库,它收集了具有多个亚细胞定位注释的蛋白质。它是免费访问。
Subcellular localization information is one of the key features to protein function research. Locating to a specific subcellular compartment is essential for a protein to function efficiently. Proteins which have multiple localizations will provide more clues. This kind of proteins may take a high proportion, even more than 35%. We have developed a database of proteins with multiple subcellular localizations, designated DBMLoc. The initial release contains 10470 multiple subcellular localization-annotated entries. Annotations are collected from primary protein databases, specific subcellular localization databases and literature texts. All the protein entries are cross-referenced to GO annotations and SwissProt. Protein-protein interactions are also annotated. They are classified into 12 large subcellular localization categories based on GO hierarchical architecture and original annotations. Download, search and sequence BLAST tools are also available on the website. DBMLoc is a protein database which collects proteins with more than one subcellular localization annotation. It is freely accessed at .
DOI: 10.1093/nar/28.1.289
发表时间: 2000-01-01
影响因子: 14.9
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