Q‐Switched Ruby Laser Treatment of Oculodermal Melanosis (Nevus of Ota)
Q‐Switched Ruby Laser Treatment of Oculodermal Melanosis (Nevus of Ota)
复制标题
Q开关红宝石激光治疗眼真皮黑变病（太田痣）
DOI：
10.1097/00006534-199610000-00004
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发表时间：
1996
影响因子：
3.6
通讯作者：
B. Achauer
中科院分区：
文献类型：
--
作者：
Cheng;Stuart J. Nelson;B. Achauer
&NA; 694 nm 的 Q 开关红宝石激光（相对于皮肤中其他光学吸收结构而言，黑色素能很好地吸收该波长）可对富含色素的细胞进行高度选择性破坏。此外，该激光器产生的 20 至 40 ns 脉冲持续时间近似于黑素体的热弛豫时间，从而将能量限制在目标上。 1991年12月至1994年12月，采用Q开关红宝石激光治疗太田痣患者47例（男11例，女36例），面部面积3×3cm2～20×20cm2。使用的能量注量从 8 到 10 J/cm2 不等，处理次数从 1 到 8 不等（平均 3.4）。根据清洁和褪色情况对结果进行评级如下：差（0%至25%）、一般（26%至50%）、良好（51%至75%）和优秀（76%至100%）。平均随访期为 15 个月。接受一种治疗的 8 名患者和接受两种治疗的 7 名患者的结果较差和/或一般。接受2次治疗的1名患者、接受3次治疗的7名患者、接受4次治疗的3名患者取得良好效果。 21 名患者在对整个病灶进行 3 次或以上治疗后取得了良好的效果。总之，该激光系统可以使患者的太田痣产生具有临床意义的消退效果，而不会出现肥厚性疤痕或正常皮肤色素沉着永久改变等并发症。 （塑料重建外科 98：784，1996。）
&NA; The Q‐switched ruby laser at 694 nm, a wavelength well absorbed by melanin relative to other optically absorbing structures in skin, causes highly selective destruction of pigment‐laden cells. In addition, the 20‐ to 40‐ns pulse duration produced by this laser approximates the thermal relaxation time for the melanosomes, thereby confining the energy to the target. The Q‐switched ruby laser was used to treat 47 patients (11 males and 36 females) with nevus of Ota during the period December 1991 to 1994. The involved facial area ranged from 3 × 3 cm2 to 20 X 20 cm2. The energy fluence used varied from 8 to 10 J/cm2, and the number of treatments ranged from 1 to 8 (mean 3.4). The results were graded on the basis of cleaning and fading as follows: poor (0 to 25 percent), fair (26 to 50 percent), good (51 to 75 percent), and excellent (76 to 100 percent). The mean follow‐up period was 15 months. Poor and/or fair results were found in 8 patients who received one treatment and 7 patients who had two treatments. Good results were seen in 1 patient who had two treatments, 7 patients who received three treatments, and 3 patients who had four treatments. Twenty‐one patients had excellent results after three or more treatments of the whole lesion. In conclusion, this laser system produces clinically significant fading of nevus of Ota in patients without complications such as hypertrophic scarring or permanent changes in the normal skin pigmentation. (Plast. Reconstr. Surg. 98: 784, 1996.)
与眼真皮黑素细胞增多症相关的脉络膜恶性黑色素瘤。
影响因子：
13.7
作者：
Gonder,JR;Shields,JA;Albert,DM
通讯作者：
Albert,DM
调Q红宝石激光治疗太田痣。
影响因子：
13.8
作者：
Taylor,CR;Flotte,TJ;Gange,RW;Anderson,RR
通讯作者：
Anderson,RR