Biological consequences of zinc deficiency in the pathomechanisms of selected diseases.

Biological consequences of zinc deficiency in the pathomechanisms of selected diseases.
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DOI:
10.1007/s00775-014-1139-0
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发表时间:
2014-10
影响因子:
3
通讯作者:
Piekoszewski, Wojciech
Piekoszewski, Wojciech
中科院分区:
化学3区
文献类型:
--
作者:
Jurowski, Kamil;Szewczyk, Bernadeta;Nowak, Gabriel;Piekoszewski, Wojciech

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从许多角度来看,锌是生物系统中最重要的微量元素之一。许多文章描述了这种金属在人体生理学和病理生理学中的众所周知的作用,但在相关文献中,缺乏锌缺乏在许多疾病中的作用的当前和可靠的综述。在这篇文章中,我们描述了锌缺乏在氧化应激控制,免疫反应,增殖,以及选定的疾病,如抑郁症,心血管疾病,糖尿病,阿尔茨海默病,威尔逊病的发病机制和病理生理学的作用。
From many points of view, zinc is one of the most important trace elements in biological systems. Many articles describe the well-known role of this metal in human physiology and pathophysiology, but in the related literature, there is a lack of current and reliable reviews of the role of zinc deficiency in many diseases. In this article, we describe the role of zinc deficiency in the oxidative stress control, immune response, proliferation, and pathogenesis and pathophysiology of selected diseases such as depression, cardiovascular diseases, diabetes mellitus, Alzheimer’s disease, and Wilson’s disease.
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