Selectivity of lipid-protein interactions

Selectivity of lipid-protein interactions
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脂质-蛋白质相互作用的选择性

DOI:
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发表时间:
1987
影响因子:
3
通讯作者:
D. Marsh
D. Marsh
中科院分区:
生物学4区
文献类型:
--
作者:
D. Marsh

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综述了测定脂质与膜蛋白相互作用选择性的自旋标记ESR法和内源荧光猝灭法。磷脂,脂肪酸和类固醇的选择性模式进行审查的各种积分蛋白质。在适当的情况下,建立相关性与特定脂质对酶活性和运输功能的影响的生化测定。
The spin label ESR and intrinsic fluorescence quenching methods of determining the selectivity of interactions of lipids with integral membrane proteins are summarized. The selectivity patterns of phospholipids, fatty acids, and steroids are reviewed for a variety of integral proteins. Where appropriate, correlations are established with biochemical assays of the effects of specific lipids on enzymatic activity and transport function.
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