Mitome: dynamic and interactive database for comparative mitochondrial genomics in metazoan animals.
Mitome: dynamic and interactive database for comparative mitochondrial genomics in metazoan animals.
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DOI：
10.1093/nar/gkm763
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发表时间：
2008-01
影响因子：
14.9
通讯作者：
Hwang UW
中科院分区：
文献类型：
--
作者：
Lee YS;Oh J;Kim YU;Kim N;Yang S;Hwang UW
Mitome是一个专门的线粒体基因组数据库，旨在方便比较分析后生动物线粒体基因组的各种特征，如碱基频率，A+T偏斜，密码子使用和基因排列模式。该数据库的一个特定功能是基于核苷酸序列、氨基酸序列或基因排列模式自动重建由用户从分类树菜单中选择的后生动物之间的系统发育关系。线粒体组还使我们能够（i）容易地找到生物体的分类位置，其完整的线粒体基因组序列是公开的;（ii）通过图形基因组浏览器获得各种后生动物的线粒体基因组特征;（iii）搜索线粒体基因排列的同源模式;（iv）在线粒体基因排列中寻找同源模式。（iv）不仅下载整个线粒体基因组的核苷酸或氨基酸序列，而且下载每个组分的核苷酸或氨基酸序列;（v）通过与PubMed的链接轻松找到有趣的参考文献。为了向用户提供一个动态的、响应式的、交互式的和更快的Web数据库，Mitome使用了两种最近突出的技术，Ajax（异步JavaScript和XML）和Web服务。有丝分裂体在分子遗传学、进化和比较细胞器基因组学等领域有着巨大的应用潜力。该数据库可在http://www.mitome.info上查阅。
Mitome is a specialized mitochondrial genome database designed for easy comparative analysis of various features of metazoan mitochondrial genomes such as base frequency, A+T skew, codon usage and gene arrangement pattern. A particular function of the database is the automatic reconstruction of phylogenetic relationships among metazoans selected by a user from a taxonomic tree menu based on nucleotide sequences, amino acid sequences or gene arrangement patterns. Mitome also enables us (i) to easily find the taxonomic positions of organisms of which complete mitochondrial genome sequences are publicly available; (ii) to acquire various metazoan mitochondrial genome characteristics through a graphical genome browser; (iii) to search for homology patterns in mitochondrial gene arrangements; (iv) to download nucleotide or amino acid sequences not only of an entire mitochondrial genome but also of each component; and (v) to find interesting references easily through links with PubMed. In order to provide users with a dynamic, responsive, interactive and faster web database, Mitome is constructed using two recently highlighted techniques, Ajax (Asynchronous JavaScript and XML) and Web Services. Mitome has the potential to become very useful in the fields of molecular phylogenetics and evolution and comparative organelle genomics. The database is available at: http://www.mitome.info.
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影响因子：
5.8
作者：
Zmasek, CM;Eddy, SR
通讯作者：
Eddy, SR
影响因子：
5.8
作者：
Li, KB
通讯作者：
Li, KB
影响因子：
6.5
作者：
Hassanin, A;Léger, N;Deutsch, J
通讯作者：
Deutsch, J
影响因子：
5.8
作者：
de Vasconcelos, ATR;Guimaraes, ACR;Russo, CAM
通讯作者：
Russo, CAM
DOI：
10.1073/pnas.77.11.6715
发表时间：
1980-01-01
期刊：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子：
--
作者：
GILES, RE;BLANC, H;WALLACE, DC
通讯作者：
WALLACE, DC