Maternal Factors Associated with Levels of Fatty Acids, Specifically n-3 PUFA during Pregnancy: ECLIPSES Study.
Maternal Factors Associated with Levels of Fatty Acids, Specifically n-3 PUFA during Pregnancy: ECLIPSES Study.
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DOI：
10.3390/nu13020317
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发表时间：
2021-01-22
期刊：
影响因子：
5.9
通讯作者：
The Eclipses Study Group
中科院分区：
文献类型：
--
作者：
Aparicio E;Martín-Grau C;Bedmar C;Serrat Orus NS;Basora J;Arija V;The Eclipses Study Group
怀孕期间的最佳脂肪酸（FA）配置，特别是二十二碳六烯酸（DHA）和二十碳五烯酸（EPA），对母亲和孩子的健康至关重要。我们的目的是确定与孕妇血清FA浓度相关的社会经济和母亲生活方式因素。对479名孕妇进行了一项纵向研究，这些孕妇在怀孕的第一（T1）和第三（T3）个月期间进行了评估。收集了有关产妇特征、食物消费和生活方式的数据。采用气相色谱-质谱联用分析血清FA浓度。多元线性回归结果显示，高文化程度和年龄与T1和/或T3时较高的EPA和DHA浓度以及较低的n-6/n-3和花生四烯酸(AA)/EPA值显著相关。在两个妊娠期，食用鱼和海鲜会增加EPA浓度，降低n-6/n-3和AA/EPA值，而食用鱼和海鲜只会增加DHA浓度。吸烟与T1期较低的DHA浓度和两个孕期较高的n-6/n-3比值有关。超重和肥胖与T1期较高的n-6/n-3比值和AA/EPA比值相关。饱和脂肪酸（SFA）和单不饱和脂肪酸（MUFA）之间没有统计学上的显著相关性。综上所述，高教育水平、年龄较大、食用鱼类、海鲜和/或不吸烟，是影响妊娠两个三个月更好的omega-3多不饱和脂肪酸（n-3 PUFA）谱的因素。需要进一步的研究来深入了解这些发现及其对健康的影响。
An optimal fatty acid (FA) profile during pregnancy, especially docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), is essential for the health of the mother and child. Our aim was to identify the socioeconomic and maternal lifestyle factors associated with serum FA concentration in pregnant women. A longitudinal study was conducted on 479 pregnant women, who were assessed during the first (T1) and third (T3) trimesters of pregnancy. Data on maternal characteristics, food consumption, and lifestyle were collected. Serum FA concentrations were analysed by a gas chromatography–mass spectrometry combination. The multiple linear regression showed that high educational level and older age were significantly associated with higher EPA and DHA concentrations and lower values of n-6/n-3 and arachidonic acid (AA)/EPA in T1 and/or T3. Regarding diet—fish and seafood consumption increased EPA concentration and reduced n-6/n-3 and AA/EPA values in both trimesters, whereas its consumption increased DHA concentration only in T1. Smoking was associated with lower DHA concentration in T1 and higher values of n-6/n-3 ratio in both trimester. Overweight and obesity were associated with higher values of n-6/n-3 ratio and AA/EPA ratio in T1. A statistically non-significant association was observed with saturated fatty acids (SFA) and monounsaturated fatty acids (MUFA). In conclusion, high educational levels, older age, fish, seafood consumption, and/or non-smoking, are factors that influence better omega-3 polyunsaturated fatty acid (n-3 PUFA) profile in both trimesters of pregnancy. Further research is needed to go in-depth into these findings and their health consequences.
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影响因子：
3.1
作者：
Arija V;Fargas F;March G;Abajo S;Basora J;Canals J;Ribot B;Aparicio E;Serrat N;Hernández-Martínez C;Aranda N
通讯作者：
Aranda N
DOI：
10.1590/s0212-16112011000200013
发表时间：
2011-04-01
期刊：
Nutrición Hospitalaria
影响因子：
--
作者：
Gómez Candela, C.;Bermejo López, L. M.ª;Loria Kohen, V.
通讯作者：
Loria Kohen, V.
影响因子：
5
作者：
Julvez, Jordi;Mendez, Michelle;Sunyer, Jordi
通讯作者：
Sunyer, Jordi
影响因子：
5.9
作者：
Jahns L;Raatz SK;Johnson LK;Kranz S;Silverstein JT;Picklo MJ
通讯作者：
Picklo MJ
DOI：
10.1016/j.plefa.2016.04.002
发表时间：
2016-06-01
影响因子：
3
作者：
Gellert, Sandra;Schuchardt, Jan Philipp;Hahn, Andreas
通讯作者：
Hahn, Andreas