'Omic approaches to preventing or managing metastatic breast cancer.

'Omic approaches to preventing or managing metastatic breast cancer.
复制标题

DOI:
10.1186/bcr2923
复制
发表时间:
2011
期刊:
Breast cancer research : BCR
影响因子:
--
通讯作者:
Gray JW
Gray JW
中科院分区:
其他
文献类型:
--
作者:
Griffith OL;Gray JW

文献摘要

参考文献

被引文献

相似文献

早期发现转移倾向的乳腺癌和残留转移癌的特征是重要的努力,以改善乳腺癌的管理。基因组规模分子分析技术的应用通过揭示与转移性疾病独特相关的分子特征,使这些互补方法成为可能。揭示这些分子特征的检测将促进解剖学、组织学和基于血液的策略的发展,这些策略可能使转移扩散之前的检测成为可能。这些特征的知识也将指导治疗策略的开发,当转移性疾病负荷低时可以应用,从而增加治愈反应的可能性。
Early detection of metastasis-prone breast cancers and characterization of residual metastatic cancers are important in efforts to improve management of breast cancer. Applications of genome-scale molecular analysis technologies are making these complementary approaches possible by revealing molecular features uniquely associated with metastatic disease. Assays that reveal these molecular features will facilitate development of anatomic, histological and blood-based strategies that may enable detection prior to metastatic spread. Knowledge of these features also will guide development of therapeutic strategies that can be applied when metastatic disease burden is low, thereby increasing the probability of a curative response.
DOI: 10.1038/nrc1299
发表时间: 2004-03
期刊: Nature reviews. Cancer
影响因子: --
作者:
通讯作者: --
DOI: 10.1038/nature08989
发表时间: 2010-04-15
期刊: Nature
影响因子: 64.8
作者:
通讯作者: --
DOI: 10.1001/jama.2011.593
发表时间: 2011-05-11
期刊: JAMA
影响因子: --
作者:
Hatzis C;Pusztai L;Valero V;Booser DJ;Esserman L;Lluch A;Vidaurre T;Holmes F;Souchon E;Wang H;Martin M;Cotrina J;Gomez H;Hubbard R;Chacón JI;Ferrer-Lozano J;Dyer R;Buxton M;Gong Y;Wu Y;Ibrahim N;Andreopoulou E;Ueno NT;Hunt K;Yang W;Nazario A;DeMichele A;O'Shaughnessy J;Hortobagyi GN;Symmans WF
通讯作者: Symmans WF
DOI: 10.1038/nature08987
发表时间: 2010-04-15
期刊: Nature
影响因子: 64.8
作者:
通讯作者: --
DOI: 10.1093/bmb/ldq011
发表时间: 2010-06-01
影响因子: 6.7
作者:
Gerges, Noha;Rak, Janusz;Jabado, Nada
通讯作者: Jabado, Nada