Electromagnetic field exposure induces rapid, transitory heat shock factor activation in human cells
Electromagnetic field exposure induces rapid, transitory heat shock factor activation in human cells
复制标题
电磁场暴露会诱导人体细胞中快速、短暂的热休克因子激活
DOI:
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发表时间:
1997
影响因子:
4
通讯作者:
R. Goodman
中科院分区:
文献类型:
--
作者:
Hana Lin;M. Opler;Mark Head;M. Blank;R. Goodman
Stimulation of human promyelocytic HL60 cells by a 60Hz magnetic field at normal growth temperatures results in heat shock factor 1 activation and heat shock element binding, a sequence of events that mediates the stress‐induced transcription of the stress gene HSP70 and increased synthesis of the stress response protein hsp70kD. Thus, the events mediating the electromagnetic field–stimulated stress response appear to be similar to those reported for other physiological stresses (e.g., hyperthermia, heavy metals, oxidative stress) and could well be the general mechanism of interaction of electromagnetic fields with cells. J. Cell. Biochem. 66:482–488, 1997. © 1997 Wiley‐Liss, Inc.
影响因子:
3.3
作者:
Lin,XH;Grako,KA;Burg,MA;Stallcup,WB
通讯作者:
Stallcup,WB
影响因子:
4
作者:
Head,MW;Hurwitz,L;Goldman,JE
通讯作者:
Goldman,JE