Human leptospirosis trends, the Netherlands, 1925-2008.
Human leptospirosis trends, the Netherlands, 1925-2008.
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DOI：
10.3201/eid1903.111260
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发表时间：
2013-03
影响因子：
11.8
通讯作者：
Hartskeerl RA
中科院分区：
文献类型：
--
作者：
Goris MG;Boer KR;Duarte TA;Kliffen SJ;Hartskeerl RA
为了增加对荷兰钩端螺旋体病的认识，并确定这种疾病随时间的变化趋势，我们分析了84年（1925-2008）的历史被动监测报告。结果发现确诊重度钩端螺旋体病2553例（平均年发病率为0.25例/10万人）。报告的钩端螺旋体病患者的总病死率为6.5%，但在此期间有所下降，可能是因为治疗方法的改善。报告的钩端螺旋体病病例中有90%是男性患者。大多数本地钩端螺旋体病感染与娱乐暴露有关，但15.5%的病例归因于导致伤害的事故和伴随的水接触。自20世纪50年代末以来，输入性感染的比例逐渐上升，2005-2008年达到53.1%。大多数（80.1%）输入性感染与体育和冒险度假活动有关。
To increase knowledge of leptospirosis in the Netherlands and identify changing trends of this disease over time, we analyzed historical passive surveillance reports for an 84-year period (1925–2008). We found that 2,553 mainly severe leptospirosis cases were diagnosed (average annual incidence rate 0.25 cases/100,000 population). The overall case-fatality rate for patients with reported leptospirosis was 6.5% but decreased over the period, probably because of improved treatment. Ninety percent of reported leptospirosis cases were in male patients. Most autochthonous leptospirosis infections were associated with recreational exposures, but 15.5% of the cases were attributed to accidents that resulted in injury and to concomitant water contact. Since the end of the 1950s, the proportion of imported infections gradually increased, reaching 53.1% of the total during 2005–2008. Most (80.1%) imported infections were associated with sporting and adventurous vacation activities.
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影响因子：
2.9
作者：
Vijayachari, P.;Sugunan, A. P.;Shriram, A. N.
通讯作者：
Shriram, A. N.
影响因子：
8.4
作者：
Baranton, G;Postic, D
通讯作者：
Postic, D
DOI：
10.1128/aem.25.6.976-980.1973
发表时间：
1973-01-01
期刊：
APPLIED MICROBIOLOGY
影响因子：
--
作者：
COLE, JR;SULZER, CR;PURSELL, AR
通讯作者：
PURSELL, AR
DOI：
10.1016/s0035-9203(34)90094-8
发表时间：
1934-01-01
影响因子：
2.2
作者：
Schuffner, W.
通讯作者：
Schuffner, W.
影响因子：
11.8
作者：
Levett, PN
通讯作者：
Levett, PN