Photo-detectors for time of flight positron emission tomography (ToF-PET).

Photo-detectors for time of flight positron emission tomography (ToF-PET).
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DOI:
10.3390/s101110484
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发表时间:
2010
期刊:
Sensors (Basel, Switzerland)
影响因子:
--
通讯作者:
Levin CS
Levin CS
中科院分区:
其他
文献类型:
--
作者:
Spanoudaki VCh;Levin CS

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我们提出了最新的进展,在光电探测器设计中采用的飞行时间正电子发射断层扫描(ToF-PET)。PET是一种分子成像模态,其收集从患者身体发射的符合(时间相关)湮灭光子对。湮灭光子探测器通常包括耦合到快速光电探测器的闪烁晶体。ToF信息提供了沿着由每个探测器对形成的线的湮灭事件的更好的定位,从而导致重建图像的信噪比(SNR)的总体改善。除了对闪烁晶体的高亮度和快速衰减时间的要求外,适当设计和选择光电探测器以及到达时间拾取方法是实现ToF-PET所需的优异时间分辨率的先决条件。我们回顾了两种类型的光电探测器用于ToF-PET:光电倍增管(PMT)和硅光电倍增管(SiPMs),特别侧重于SiPMs。
We present the most recent advances in photo-detector design employed in time of flight positron emission tomography (ToF-PET). PET is a molecular imaging modality that collects pairs of coincident (temporally correlated) annihilation photons emitted from the patient body. The annihilation photon detector typically comprises a scintillation crystal coupled to a fast photo-detector. ToF information provides better localization of the annihilation event along the line formed by each detector pair, resulting in an overall improvement in signal to noise ratio (SNR) of the reconstructed image. Apart from the demand for high luminosity and fast decay time of the scintillation crystal, proper design and selection of the photo-detector and methods for arrival time pick-off are a prerequisite for achieving excellent time resolution required for ToF-PET. We review the two types of photo-detectors used in ToF-PET: photomultiplier tubes (PMTs) and silicon photo-multipliers (SiPMs) with a special focus on SiPMs.
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