Plant phenolics: extraction, analysis and their antioxidant and anticancer properties.
Plant phenolics: extraction, analysis and their antioxidant and anticancer properties.
复制标题
DOI：
10.3390/molecules15107313
复制
发表时间：
2010-10-21
期刊：
影响因子：
--
通讯作者：
Mumper RJ
中科院分区：
文献类型：
--
作者：
Dai J;Mumper RJ
酚类物质在植物界广泛分布，是植物中含量最丰富的次生代谢产物。植物多酚因其强大的抗氧化特性以及在预防癌症等多种氧化应激相关疾病方面的显著效果而受到越来越多的关注。在过去几年中，对不同植物中酚类化合物或提取物的鉴定和开发已成为健康和医学相关研究的一个主要领域。本综述对酚类物质的提取、纯化、分析和定量以及它们的抗氧化特性进行了更新且全面的概述。此外，还综述了酚类物质在体外和体内动物模型中的抗癌作用，包括近期的人类干预研究。最后，讨论了涉及抗氧化和促氧化活性以及干扰细胞功能的可能作用机制。
Phenolics are broadly distributed in the plant kingdom and are the most abundant secondary metabolites of plants. Plant polyphenols have drawn increasing attention due to their potent antioxidant properties and their marked effects in the prevention of various oxidative stress associated diseases such as cancer. In the last few years, the identification and development of phenolic compounds or extracts from different plants has become a major area of health- and medical-related research. This review provides an updated and comprehensive overview on phenolic extraction, purification, analysis and quantification as well as their antioxidant properties. Furthermore, the anticancer effects of phenolics in-vitro and in-vivo animal models are viewed, including recent human intervention studies. Finally, possible mechanisms of action involving antioxidant and pro-oxidant activity as well as interference with cellular functions are discussed.
登录
查看更多内容
影响因子：
6.4
作者：
Afaq, F;Saleem, M;Mukhtar, H
通讯作者：
Mukhtar, H
影响因子：
9.7
作者：
Agullo, G;GametPayrastre, L;Remsey, C
通讯作者：
Remsey, C
影响因子：
3.6
作者：
Afaq F;Zaid MA;Khan N;Dreher M;Mukhtar H
通讯作者：
Mukhtar H
影响因子：
8.4
作者：
Albu, S;Joyce, E;Mason, TJ
通讯作者：
Mason, TJ
影响因子：
6.1
作者：
Asami, DK;Hong, YJ;Mitchell, AE
通讯作者：
Mitchell, AE