Southern Hemisphere Influenza and Vaccine Effectiveness Research and Surveillance.
Southern Hemisphere Influenza and Vaccine Effectiveness Research and Surveillance.
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DOI：
10.1111/irv.12315
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发表时间：
2015-07
影响因子：
4.4
通讯作者：
Widdowson MA
中科院分区：
文献类型：
--
作者：
Huang QS;Turner N;Baker MG;Williamson DA;Wong C;Webby R;Widdowson MA
2009年甲型H1N1流感pdm09大流行突出表明，需要改进科学知识，以支持更好地防范大流行和控制季节性流感。南半球流感和疫苗有效性研究与监测（SHIVERS）项目是一项为期5年（2012-2016）的多机构和多学科合作项目，旨在衡量流感和其他具有公共卫生重要性的呼吸道传染病的疾病负担、流行病学、病原学、危险因素、免疫学、疫苗接种有效性和其他预防策略。建立了两个积极的、前瞻性的、基于人群的监测系统，用于监测急性呼吸道疾病住院患者和在哨点全科就诊的入组患者的流感和其他呼吸道病原体。2015年，一项血清流行病学研究将使用来自相同做法的患者样本。这些数据将提供从无症状感染到严重住院疾病和死亡的疾病负担和风险因素以及相关经济负担的全面情况。前两年（2012-2013年）的结果为以下方面提供了科学证据：(a)由于流感住院率高，支持改变新西兰对幼儿的疫苗接种政策；(b)协助修订世界卫生组织用于全球流感监测的严重急性呼吸道疾病病例定义；(c)在预防与流感有关的咨询和住院治疗中，利用疫苗有效性评估部分促进疫苗株的选择。总而言之，SHIVERS为支持季节性流感控制和大流行防范以及应对其他新发/地方性呼吸道相关感染提供了宝贵的国际平台。
The 2009 influenza A(H1N1)pdm09 pandemic highlighted the need for improved scientific knowledge to support better pandemic preparedness and seasonal influenza control. The Southern Hemisphere Influenza and Vaccine Effectiveness Research and Surveillance (SHIVERS) project, a 5-year (2012–2016) multiagency and multidisciplinary collaboration, aimed to measure disease burden, epidemiology, aetiology, risk factors, immunology, effectiveness of vaccination and other prevention strategies for influenza and other respiratory infectious diseases of public health importance. Two active, prospective, population-based surveillance systems were established for monitoring influenza and other respiratory pathogens among those hospitalized patients with acute respiratory illness and those enrolled patients seeking consultations at sentinel general practices. In 2015, a sero-epidemiological study will use a sample of patients from the same practices. These data will provide a full picture of the disease burden and risk factors from asymptomatic infections to severe hospitalized disease and deaths and related economic burden. The results during the first 2 years (2012–2013) provided scientific evidence to (a) support a change to NZ's vaccination policy for young children due to high influenza hospitalizations in these children; (b) contribute to the revision of the World Health Organization's case definition for severe acute respiratory illness for global influenza surveillance; and (c) contribute in part to vaccine strain selection using vaccine effectiveness assessment in the prevention of influenza-related consultations and hospitalizations. In summary, SHIVERS provides valuable international platforms for supporting seasonal influenza control and pandemic preparedness, and responding to other emerging/endemic respiratory-related infections.
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影响因子：
8.8
作者：
Gaunt, E. R.;Harvala, H.;Simmonds, P.
通讯作者：
Simmonds, P.
影响因子：
5.1
作者：
Dawood, Fatimah S.;Fiore, Anthony;Finelli, Lyn
通讯作者：
Finelli, Lyn
影响因子：
3.7
作者：
Fuller, James A.;Summers, Aimee;Feikin, Daniel R.
通讯作者：
Feikin, Daniel R.
影响因子：
3.6
作者：
Baker, M;McNicholas, A;Lennon, D
通讯作者：
Lennon, D
影响因子：
5.5
作者：
Foppa, Ivo M.;Haber, Michael;Shay, David K.
通讯作者：
Shay, David K.