A Meta-Analysis of the Association between Diabetes Mellitus and Traditional Chinese Medicine Constitution.
A Meta-Analysis of the Association between Diabetes Mellitus and Traditional Chinese Medicine Constitution.
复制标题
糖尿病与中医体质关联性的Meta分析
DOI：
10.1155/2021/6390530
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Wang Q
中科院分区：
文献类型：
--
作者：
Bai F;Luo H;Wang L;Zhu L;Guan Y;Zheng Y;Li L;Wang Q
探讨糖尿病中医体质类型的分布情况，为糖尿病的防治提供循证医学依据。
检索了PubMed、Embase、Web of Science以及三个中文数据库，纳入有关糖尿病与中医体质关系的研究文献。使用RStudio软件对横断面文献进行单率研究，使用Review Manager 5.3软件对糖尿病患者和非糖尿病患者人群进行对照荟萃分析。两名独立评审员评估了研究数据的方法学质量。主要结果包括糖尿病患者人群中体质类型的分布以及两者之间的比值比（OR）。效应量以比例或带有95%置信区间（CI）的比值比表示。
87篇文献共纳入28781例糖尿病病例。阴虚、痰湿和气虚分别占糖尿病总病例数的18%（95%置信区间为（15%，20%），P < 0.01）、17%（95%置信区间为（15%，19%），P < 0.01）和13%（95%置信区间为（11%，15%），P < 0.01）。阴虚和痰湿体质人群患糖尿病的风险分别比其他体质人群高3.06倍（95%置信区间为（1.38 - 6.78），P = 0.006）和1.89倍（95%置信区间为（1.05 - 3.42），P = 0.03）。糖尿病患者的中医体质分布在不同地区和年龄存在显著差异。
阴虚和痰湿是糖尿病患者常见的体质类型，也可能是糖尿病的危险因素。平和体质可能是糖尿病的保护因素。需要设计更多高质量的队列研究和病例对照研究，以便为评估糖尿病与中医体质之间的相关性提供更有价值的循证依据。
To explore the distribution of constitution types of diabetes mellitus (DM) in traditional Chinese medicine (TCM) and to provide evidence-based medicine basis for the prevention and treatment of diabetes. PubMed, Embase, Web of Science, and three Chinese databases were searched to include research literature on the relationship between diabetes and TCM constitution. The single rate study of cross-sectional literature was conducted with RStudio software, and the control meta-analysis of the diabetic and nondiabetic population was performed with Review Manager 5.3 software. Two independent reviewers assessed the methodological quality of the studies' data. The main outcomes included the distribution of constitutional types in the diabetic population and the odds ratio (OR) between the two. Effect sizes are expressed as proportions or ORs with 95% confidence intervals (CI). A total of 28,781 diabetic cases were included in 87 articles. Yin-deficiency, phlegm-dampness, and qi-deficiency accounted for 18% (95% CI (15%, 20%), P < 0.01), 17% (95% CI (15%, 19%), P < 0.01), and 13% (95% CI (11%, 15%), P < 0.01) of the total diabetic cases. The risk of diabetes in people with yin-deficiency and phlegm-dampness was 3.06 (95% CI (1.38–6.78), P=0.006) and 1.89 (95%CI (1.05–3.42), P=0.03) times higher than that in those with other constitutions, respectively. The distribution of TCM constitution of DM patients varied significantly in different regions and ages. Yin-deficiency and phlegm-dampness are the common constitution types of diabetic people, and they may also be the risk factors of diabetes. Balanced constitution may be a protective factor of diabetes. More high-quality cohort and case-control studies need to be designed to provide more valuable evidence-based basis for assessing the correlation between DM and TCM constitution.
影响因子：
5.1
作者：
Guariguata, L.;Whiting, D. R.;Shaw, J. E.
通讯作者：
Shaw, J. E.
中医在保健防病中的作用：体质理论的应用
影响因子：
5.7
作者：
Li, Lingru;Yao, Haiqiang;Wang, Qi
通讯作者：
Wang, Qi