Muscle sympathetic nerve activity during handgrip and post-handgrip muscle ischemia after exposure to simulated microgravity in humans
Muscle sympathetic nerve activity during handgrip and post-handgrip muscle ischemia after exposure to simulated microgravity in humans
复制标题
人类暴露于模拟微重力后握力期间和握力后肌肉缺血的肌肉交感神经活动
DOI：
10.1016/s0304-3940(99)00995-7
复制
发表时间：
2000
影响因子：
2.5
通讯作者：
T. Mano
中科院分区：
文献类型：
--
作者：
A. Kamiya;S. Iwase;Daisaku Michikamia;Qian;T. Mano
为探讨6 °头低位卧床（HDBR）对前臂等长运动引起的血管交感神经反应的影响，16名20-36岁的健康男性受试者在HDBR前和HDBR后14天进行了30%最大随意收缩的随意等长握力（HG）直至疲劳，随后进行了2min的握力后肌肉缺血（PHGMI），袖带充气250 mmHg。疲劳时间和最大随意HG力不受HDBR的影响。HDBR后，运动前基线肌肉交感神经活动（MSNA，通过显微神经描记术测量）、心率（通过心电图测量）和平均血压（通过Portapres测量）增加。HDBR后HG组MSNA升高幅度相似，PHGMI组明显低于HG组（P <0.01）。HDBR不影响HG和PHGMI时心率和平均血压的反应。这些结果表明，肌肉代谢反射的幅度在等长前臂运动可能会减弱后，14天的模拟微重力。
To examine the effect of 6° head-down bed rest (HDBR) on vasomotor sympathetic responses to isometric forearm exercise, 16 healthy male subjects aged 20–36 years performed voluntary isometric handgrip (HG) at 30% of maximal voluntary contraction until fatigue, followed by 2 min of post-handgrip muscle ischemia (PHGMI) with 250 mmHg of cuff inflation, before and after 14 days of HDBR. Time to fatigue and maximal voluntary HG force were not affected by HDBR. Pre-exercise baseline muscle sympathetic nerve activity (MSNA, measured by microneurography), heart rate (measured by electrocardiogram) and mean blood pressure (measured by Portapres) increased after HDBR. Increases in MSNA were similar during HG but significantly lower during PHGMI (P<0.01) after HDBR. Responses of heart rate and mean blood pressure during HG and PHGMI were not affected by HDBR. These results suggest that the magnitude of muscle metaboreflex during isometric forearm exercise might be attenuated after 14 days of simulated microgravity.
在运动引起的动脉压升高期间，动脉压力反射缓冲交感神经激活。
DOI：
10.1172/jci114916
发表时间：
1990
期刊：
The Journal of clinical investigation
影响因子：
--
作者：
Scherrer,U;Pryor,SL;Bertocci,LA;Victor,RG
通讯作者：
Victor,RG
人类运动过程中肌肉交感神经活动的调节。
影响因子：
5.7
作者：
Seals,DR;Victor,RG
通讯作者：
Victor,RG
影响因子：
3.3
作者：
FRITSCHYELLE, JM;CHARLES, JB;ECKBERG, DL
通讯作者：
ECKBERG, DL