Longitudinal assessment of network reorganizations and language recovery in postoperative patients with glioma.
Longitudinal assessment of network reorganizations and language recovery in postoperative patients with glioma.
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DOI：
10.1093/braincomms/fcac046
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发表时间：
2022
影响因子：
4.8
通讯作者：
Wu J
中科院分区：
文献类型：
--
作者：
Yuan B;Zhang N;Gong F;Wang X;Yan J;Lu J;Wu J
对于位于或邻近语言功能皮层的胶质瘤患者，强调保留语言功能的清醒手术是首选。然而，术后语言功能结果的脑网络基础在很大程度上仍然未知。在这项工作中，34例接受清醒手术的左脑胶质瘤患者在手术前后评估了语言功能和静息状态网络特性。我们发现有28名患者的语言功能在术后3个月内恢复到基线评分的至少80%，或在术后6个月内恢复到85%。对于这些患者，语言功能的自发恢复与语言和认知控制网络的变化同步，但与其他网络无关。具体而言，与基线值相比，语言功能和全局网络特性在术后1个月内最差，并在术后6个月内逐渐恢复。连接的恢复是肿瘤位置依赖性的，并归因于同半球和半球间的连接。相比之下，对于6名语言功能恢复不佳的患者，在手术前观察到严重的网络中断，并持续到慢性期。这项研究表明，胶质瘤术后患者的功能网络正常化和自发语言恢复是同步的。对于涉及语言网络的胶质瘤患者，Yuan等人研究了语言功能自发恢复的不同时间过程的术后脑网络基础。个体和网络特异性的自发语言恢复与语言和认知控制网络的变化同步。
For patients with glioma located in or adjacent to the linguistic eloquent cortex, awake surgery with an emphasis on the preservation of language function is preferred. However, the brain network basis of postoperative linguistic functional outcomes remains largely unknown. In this work, 34 patients with left cerebral gliomas who underwent awake surgery were assessed for language function and resting-state network properties before and after surgery. We found that there were 28 patients whose language function returned to at least 80% of the baseline scores within 3 months after surgery or to 85% within 6 months after surgery. For these patients, the spontaneous recovery of language function synchronized with changes within the language and cognitive control networks, but not with other networks. Specifically, compared with baseline values, language functions and global network properties were the worst within 1 month after surgery and gradually recovered within 6 months after surgery. The recovery of connections was tumour location dependent and was attributed to both ipsihemispheric and interhemispheric connections. In contrast, for six patients whose language function did not recover well, severe network disruptions were observed before surgery and persisted into the chronic phase. This study suggests the synchronization of functional network normalization and spontaneous language recovery in postoperative patients with glioma. For patients with glioma involving language networks, Yuan et al. investigated postoperative brain network bases for diverse time courses of spontaneous recovery of language functions. The spontaneous language recovery individually and network-specifically synchronized with the changes of language and cognitive control networks.
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影响因子：
19.9
作者：
Fedorenko, Evelina;Thompson-Schill, Sharon L.
通讯作者：
Thompson-Schill, Sharon L.
人脑网络组图谱：基于连接架构的新大脑图谱
DOI：
10.1093/cercor/bhw157
发表时间：
2016-08
期刊：
Cerebral cortex (New York, N.Y. : 1991)
影响因子：
--
作者：
Fan L;Li H;Zhuo J;Zhang Y;Wang J;Chen L;Yang Z;Chu C;Xie S;Laird AR;Fox PT;Eickhoff SB;Yu C;Jiang T
通讯作者：
Jiang T
影响因子：
4.8
作者：
Hart, Michael G.;Romero-Garcia, Rafael;Suckling, John
通讯作者：
Suckling, John
影响因子：
11
作者：
Duffau, H;Capelle, L;Van Effenterre, R
通讯作者：
Van Effenterre, R
DOI：
10.1007/978-3-211-72283-1_1
发表时间：
2008-01-01
期刊：
ADVANCES AND TECHNICAL STANDARDS IN NEUROSURGERY, VOL 33
影响因子：
--
作者：
Duffau, H.
通讯作者：
Duffau, H.