Neurocognitive correlates of obesity and obesity-related behaviors in children and adolescents.

Neurocognitive correlates of obesity and obesity-related behaviors in children and adolescents.
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DOI:
10.1038/ijo.2013.142
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发表时间:
2014-04
影响因子:
4.9
通讯作者:
Boutelle, K. N.
Boutelle, K. N.
中科院分区:
医学2区
文献类型:
--
作者:
Liang, J.;Matheson, B. E.;Kaye, W. H.;Boutelle, K. N.

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在过去的几十年里,儿童肥胖率急剧上升。虽然肥胖与成人神经认知功能较差有关,但对儿童和青少年的这种关系知之甚少。因此,我们进行了一个系统的审查,以检查肥胖和肥胖相关的行为与神经认知功能的青年之间的关系。我们使用PsycInfo,PubMed,Medline和Google Scholar回顾了1976年至2013年的文章。检索词包括认知功能、神经认知功能/表现、执行功能、冲动性、自我调节、努力控制、认知控制、抑制、延迟满足、记忆、注意力、语言、运动、视觉空间、学业成绩、肥胖、超重、体重指数、腰臀比、肥胖和体脂。如果参与者有已知影响认知功能的健康问题,研究使用成像作为唯一的结局指标,它们是非同行评审的论文,论文,综述论文,评论,或者它们是非英语文章,则文章被排除在外。67项研究符合本综述的纳入标准。总的来说,我们发现的数据支持肥胖和神经认知功能的各个方面,如执行功能,注意力,视觉空间表现和运动技能之间的负相关关系。现有文献对肥胖、一般认知功能、语言、学习、记忆和学业成绩的影响褒贬不一。执行功能障碍与肥胖相关的行为有关,如摄入量增加,饮食失调和身体活动减少。体力活动与运动技能呈正相关。需要更多的纵向研究来确定这种关系的方向性,指出儿童发展中的关键干预时间段,并为有效的治疗方案提供信息。
Childhood obesity rates have risen dramatically over the past few decades. Although obesity has been linked to poorer neurocognitive functioning in adults, much less is known about this relationship in children and adolescents. Therefore, we conducted a systematic review to examine the relationship between obesity and obesity-related behaviors with neurocognitive functioning in youth. We reviewed articles from 1976 to 2013 using PsycInfo, PubMed, Medline and Google Scholar. Search terms included cognitive function, neurocognitive function/performance, executive function, impulsivity, self-regulation, effortful control, cognitive control, inhibition, delayed gratification, memory, attention, language, motor, visuo-spatial, academic achievement, obesity, overweight, body mass index, waist-hip ratio, adiposity and body fat. Articles were excluded if participants had health problems known to affect cognitive functioning, the study used imaging as the only outcome measure, they were non-peer-reviewed dissertations, theses, review papers, commentaries, or they were non-English articles. Sixty-seven studies met inclusion criteria for this review. Overall, we found data that support a negative relationship between obesity and various aspects of neurocognitive functioning, such as executive functioning, attention, visuo-spatial performance, and motor skill. The existing literature is mixed on the effects among obesity, general cognitive functioning, language, learning, memory, and academic achievement. Executive dysfunction is associated with obesity-related behaviors, such as increased intake, disinhibited eating, and less physical activity. Physical activity is positively linked with motor skill. More longitudinal research is needed to determine the directionality of such relationships, to point towards crucial intervention time periods in the development of children, and to inform effective treatment programs.
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